Chemicals list & Research Gallery

Indoline
CAS number: 496-15-1
Indoline is a heterocyclic organic compound, which is a bicyclic structure formed by the fusion of a benzene ring and a five-membered nitrogen-containing ring (pyrrolidine ring).
Synthesis of indoline 7.
Synthesis of indoline 7.
Aerobic oxidation of an indoline derivative.
Aerobic oxidation of an indoline derivative.
Ergothioneine
CAS number: 497-30-3
Ergothioneine (ERG) is an unusual thio-histidine betaine amino acid that has potent antioxidant activities.
In solution, L-ergothioneine (EGT; 2-mercaptohistidine trimethylbetaine) exists as a tautomer between its thiol and thione forms.
In solution, L-ergothioneine (EGT; 2-mercaptohistidine trimethylbetaine) exists as a tautomer between its thiol and thione forms.
Tissue expression of the ERGOTHIONEINE transporter, OCTN1, analyzed by real-time PCR adapted from 2 independent sources (Grundemann et al. 2005; National Academy of Sciences and Taubert et al. 2009; BMJ Journals). Data are relative to mRNA level of the ileum for each set.
Tissue expression of the ERGOTHIONEINE transporter, OCTN1, analyzed by real-time PCR adapted from 2 independent sources (Grundemann et al. 2005; National Academy of Sciences and Taubert et al. 2009; BMJ Journals). Data are relative to mRNA level of the ileum for each set.
Possible roles and interactions of Ergothioneine in vivo. Functional roles as an antioxidant are highlighted in yellow, anti-inflammatory agent in green, protectant against radiation in blue and roles in disease in orange.
Possible roles and interactions of Ergothioneine in vivo. Functional roles as an antioxidant are highlighted in yellow, anti-inflammatory agent in green, protectant against radiation in blue and roles in disease in orange.
Since its first isolation in 1905, there was initially significant interest in Ergothioneine, however the interest waned until the discovery of its transporter (ETT/OCTN1) in 2005 and has since been the focus of intense research.
Since its first isolation in 1905, there was initially significant interest in Ergothioneine, however the interest waned until the discovery of its transporter (ETT/OCTN1) in 2005 and has since been the focus of intense research.
High expression of the transporter, and hence high levels of Ergothioneine, is observed in certain cells (e.g. blood cells, bone marrow, ocular tissues, brain etc.) that are likely predisposed to oxidative stress, although other tissues can accumulate high levels of ET with sustained administration.
High expression of the transporter, and hence high levels of Ergothioneine, is observed in certain cells (e.g. blood cells, bone marrow, ocular tissues, brain etc.) that are likely predisposed to oxidative stress, although other tissues can accumulate high levels of ET with sustained administration.
Norbornene
CAS number: 498-66-8
Norbornene, also known as bicyclo[2.2.1]hept-2-ene, is a cyclic alkene with a dense three-dimensional structure: a cyclohexene ring with a bridging methylene in the para-position.
Schematic representation of the repeating units of poly(N-(1-adamantyl)-exo-norbornene-5,6-dicarboximide) (M1), poly(N-cyclohexyl-exo-norbornene-5,6-dicarboximide) (M2), poly-(N-phenyl-exo-norbornene-5,6-dicarboximide) (M3), and copolymers of N-(1-adamantyl)-exo-norbornene-5,6-dicarboximide with norbornene.
Schematic representation of the repeating units of poly(N-(1-adamantyl)-exo-norbornene-5,6-dicarboximide) (M1), poly(N-cyclohexyl-exo-norbornene-5,6-dicarboximide) (M2), poly-(N-phenyl-exo-norbornene-5,6-dicarboximide) (M3), and copolymers of N-(1-adamantyl)-exo-norbornene-5,6-dicarboximide with norbornene.
Formaldehyde
CAS number: 50-00-0
Formaldehyde was described in the year 1855 by the Russian scientist Alexander Michailowitsch Butlerow. At room temperature, formaldehyde is a colorless, flammable gas that has a distinct, pungent smell.
Scheme 3 shows the procedure used for the synthesis of 4. Subjection of 3'-chloropropiophenone (10a) to Mannich reaction conditions with aqueous formaldehyde and dimethylamine gave 13. The methiodide 14 was obtained by alkylation of 13 with iodomethane. Treatment of 14 with tert-butylamine gave first a mixture of 15 and the desired 4. Subjection of the mixture to excess tert-butylamine provided the desired target compound.
Scheme 3 shows the procedure used for the synthesis of 4. Subjection of 3'-chloropropiophenone (10a) to Mannich reaction conditions with aqueous formaldehyde and dimethylamine gave 13. The methiodide 14 was obtained by alkylation of 13 with iodomethane. Treatment of 14 with tert-butylamine gave first a mixture of 15 and the desired 4. Subjection of the mixture to excess tert-butylamine provided the desired target compound.
Cocaine
CAS number: 50-36-2
Cocaine is an intense, euphoria-producing stimulant drug with strong addictive potential.
Chemical structures of cocaine and other tropane-based DAT inhibitors.
Chemical structures of cocaine and other tropane-based DAT inhibitors.
6-Mercaptopurine
CAS number: 50-44-2
Mercaptopurine (also known as 6-mercaptopurine or 6-MP) is used for acute lymphoblastic leukemia (ALL).
Structures of 6-mercaptopurine and thioguanine and their 5-aza-7-deaza analogs.
Structures of 6-mercaptopurine and thioguanine and their 5-aza-7-deaza analogs.
L-Ascorbic acid
CAS number: 50-81-7
L-ascorbic acid (vitamin C) is a powerful water-soluble antioxidant, essential for the correct functioning of the body.
Effect of Compounds on Ferric Ion and Ascorbic Acid Induced Lipid Peroxidation
Effect of Compounds on Ferric Ion and Ascorbic Acid Induced Lipid Peroxidation
The novel 1,2,4-triazole-3-carboxamide and 4,5-disubstituted-imidazole L-ascorbic acid (1, 2, 3, 5, 6 and 9) and imino-ascorbic acid (4, 7 and 8) derivatives.
The novel 1,2,4-triazole-3-carboxamide and 4,5-disubstituted-imidazole L-ascorbic acid (1, 2, 3, 5, 6 and 9) and imino-ascorbic acid (4, 7 and 8) derivatives.
Glucose
CAS number: 50-99-7
Glucose is a simple sugar that serves as the body's primary source of energy. It's a type of carbohydrate, and is found in foods like fruits, vegetables, and grains.
Systematic chemical modification of the glucopyranoside backbone inhibits the growth of glioblastoma cells.
Systematic chemical modification of the glucopyranoside backbone inhibits the growth of glioblastoma cells.
The chiral diphosphite ligands with the pyranoside backbone of galactose (L1 and L2) and glucose (L3 and L4).
The chiral diphosphite ligands with the pyranoside backbone of galactose (L1 and L2) and glucose (L3 and L4).
Ethyl quinoline-3-carboxylate
CAS number: 50741-46-3
Ethyl quinoline-3-carboxylate is an organic compound that is the ethyl ester of quinoline-3-carboxylic acid, which means it contains a quinoline ring system with a carboxylic acid group and an ethyl group attached to the third carbon of the quinoline ring.
Synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid ethyl ester 3.
Synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid ethyl ester 3.
Synthetic strategy for the synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid ethyl ester 3.
Synthetic strategy for the synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid ethyl ester 3.
Podophyllotoxin
CAS number: 518-28-5
Podophyllotoxin is an aryltetralin-type lignan isolated from species of Podophyllum. Two most common sources are the rhizomes of Podophyllum peltatum (American mayapple) and Sinopodophyllum hexandrum Royle (Barberry family).
Podophyllotoxin derivatives.
Podophyllotoxin derivatives.
Structures of podophyllotoxin, NPF, GL331, TOP 53, NK61, and VP-16.
Structures of podophyllotoxin, NPF, GL331, TOP 53, NK61, and VP-16.