Chemicals list & Research Gallery

Lithium diisopropylamide
CAS number: 4111-54-0
Lithium diisopropylamide (LDA) is a prominent reagent used in organic synthesis. It is a hindered non-nucleophilic strong base that abstracts hydrogen from active carbon.
Catalytic asymmetric synthesis of (S)-verapamil. LDA=lithium diisopropylamide.
Catalytic asymmetric synthesis of (S)-verapamil. LDA=lithium diisopropylamide.
Azide–enolate [3+2] cycloaddition reactions implicated in amide and triazoline synthesis. LDA=lithium diisopropylamide, LHMDS=lithium hexamethyldisilazide.
Azide–enolate [3+2] cycloaddition reactions implicated in amide and triazoline synthesis. LDA=lithium diisopropylamide, LHMDS=lithium hexamethyldisilazide.
Apomorphine hydrochloride hemihydrate
CAS number: 41372-20-7
Apomorphine hydrochloride hemihydrate is a medication, specifically a dopamine agonist, used primarily in the treatment of Parkinson's disease and, in some cases, erectile dysfunction.
Quinolide (4) has structural features of both ergoline and apomorphine.
Quinolide (4) has structural features of both ergoline and apomorphine.
Tetrabutylammonium fluoride
CAS number: 429-41-4
Tetrabutylammonium fluoride is a fluoride salt and a tetrabutylammonium salt. It has a role as a phase-transfer catalyst.
Preparation of alkene 34 (TBAF = tetrabutylammonium fluoride).
Preparation of alkene 34 (TBAF = tetrabutylammonium fluoride).
Proposed six membered transition state mechanism
Proposed six membered transition state mechanism
Ring Opening of α,β-Epoxyalcohols Using TBAF Compared to Other Methods
Ring Opening of α,β-Epoxyalcohols Using TBAF Compared to Other Methods
Glycine ethyl ester
CAS number: 459-73-4
Glycine ethyl ester (GEE) is used in conjunction with N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide (EDC) for carboxyl-footprinting studies of proteins.
Attempted amino acid coupling: glycine ethyl ester, N,N'-dicyclohexyl carbodiimide (DCCI) or 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide (EDAC), 1-hydroxybenzotriazole (HOBt), water, room temperature.
Attempted amino acid coupling: glycine ethyl ester, N,N'-dicyclohexyl carbodiimide (DCCI) or 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide (EDAC), 1-hydroxybenzotriazole (HOBt), water, room temperature.
Benzyne
CAS number: 462-80-6
Benzyne is a highly reactive organic molecule that has not been isolated. It's an extremely reactive intermediate, meaning it's not stable enough to be isolated but can be observed as a fleeting species during certain chemical reactions.
Possible Products of the Reaction of Benzyne and P-Alkenyl-λ5-phosphazenes
Possible Products of the Reaction of Benzyne and P-Alkenyl-λ5-phosphazenes
Allene
CAS number: 463-49-0
An allene is an organic molecule characterized by two adjacent carbon-carbon double bonds. It's also known as a cumulated diene.
Substrate scope of the orthoboration reaction. Reaction conditions: propadiene 1 (1 eq.), BnNH2 (5 mol%), PPh3 (10 mol%), B2pin2 (1.1 eq.), CuSO4 (1 mol%). a Using 1% TPGS-750-M. b Using 3:1 toluene:water as solvent.
Substrate scope of the orthoboration reaction. Reaction conditions: propadiene 1 (1 eq.), BnNH2 (5 mol%), PPh3 (10 mol%), B2pin2 (1.1 eq.), CuSO4 (1 mol%). a Using 1% TPGS-750-M. b Using 3:1 toluene:water as solvent.
(-)-Normorphine
CAS number: 466-97-7
Normorphine is a conjugate of morphine that is excreted renally, accounting for approximately 5% to 10% of the total excretion of morphine in the body.
Normorphine derivatives.
Normorphine derivatives.
Ergoline
CAS number: 478-88-6
Ergoline is a chemical compound that forms the core structure of a class of alkaloids found in ergot and other fungi. These alkaloids, including those found in ergot, have a range of uses, from treating migraines to inducing uterine contractions.
Quinolide (4) has structural features of both ergoline and apomorphine.
Quinolide (4) has structural features of both ergoline and apomorphine.
Khellinone
CAS number: 484-51-5
Khellinone, a naturally occurring compound derived from the plant Ammi visnaga, is classified as a benzofuran derivative.
Figure 1. (A) Structures of correolide, a representative cyclohexyl benzamide and the 5-phenylalokoxypsoralen Psora-4. (B) Structures of khellinone 1a and khellin 1b. The 7-position in khellinone corresponds to the 9-position in khellin as indicated in Table 1.
Figure 1. (A) Structures of correolide, a representative cyclohexyl benzamide and the 5-phenylalokoxypsoralen Psora-4. (B) Structures of khellinone 1a and khellin 1b. The 7-position in khellinone corresponds to the 9-position in khellin as indicated in Table 1.
Pseudo-symmetry in the khellinone analogues.
Pseudo-symmetry in the khellinone analogues.
α-Kainic acid
CAS number: 487-79-6
Kainic acid is a dicarboxylic acid, a pyrrolidinecarboxylic acid, a L-proline derivative and a non-proteinogenic L-alpha-amino acid. α-Kainic acid is a neuroexcitatory molecule and a cyclic analog of L-glutamate, first isolated from the marine alga Digenea simplex. It's a key member of the kainoid family and is used in neuropharmacology research to mimic neurological disorders like epilepsy, Alzheimer's, and Huntington's disease.
Transmembrane currents induced in Purkinje neurons by different doses of glutamate and kainic acid (KA).
Transmembrane currents induced in Purkinje neurons by different doses of glutamate and kainic acid (KA).
Comparative potentiation of kainic acid (KA) and glutamate responses in Purkinje neurons by CT and 3.
Comparative potentiation of kainic acid (KA) and glutamate responses in Purkinje neurons by CT and 3.
Concentration dependence of 3 effect on the currents induced by different kainate doses.
Concentration dependence of 3 effect on the currents induced by different kainate doses.
Effect of CT (cyclothiazide) and 3 on dose-dependent response for the currents induced by kainic acid in Purkinje neurons.
Effect of CT (cyclothiazide) and 3 on dose-dependent response for the currents induced by kainic acid in Purkinje neurons.
Comparative effect of different doses of CT (cyclothiazide) and 1 on currents, induced by the fixed concentration of kainic acid (KA).
Comparative effect of different doses of CT (cyclothiazide) and 1 on currents, induced by the fixed concentration of kainic acid (KA).