Chemicals list & Research Gallery
CAS number: 76-05-1
Trifluoroacetic acid is a monocarboxylic acid that is the trifluoro derivative of acetic acid. It has a role as a reagent and a human xenobiotic metabolite.
Synthesis of 6c. Mes: 2,4,6-trimethylphenyl, TFA: trifluoroacetic acid.
Synthesis of β-LEAP. DIPEA=N,N’-diisopropylethylamine, NMM=4-methylmorpholine, HATU=O-(7-azabenzotriazol-1-yl)-N,N,N’,N’-tetramethyluronium hexafluorophosphate, TEA=triethylamine, TFA=trifluoroacetic acid.
Iodine-mediated oxidation of ynamides (Boc = tert-butoxycarbonyl, TFA = trifluoroacetic acid).
CAS number: 7601-90-3
Perchloric acid is a strong acid used for complete digestions of organic material. It is normally supplied in bottles of up to one gallon in capacity at 70-72% strength. In many respects, its hazards are similar to those of nitric acid, as both are strong oxidants.
FT-IR spectra of silica-supported perchloric acid (A), perchlorate anion (B), and SiO2 (C).
CAS number: 766-90-5
Cis-beta-methylstyrene (also known as (Z)-1-phenyl-1-butene) is an organic compound belonging to the class of alkenylbenzenes. It features a styrene-like structure with a methyl group attached to the beta-carbon of the vinyl side chain in the cis (Z) configuration, meaning the phenyl ring and the methyl group are on the same side of the double bond.
![LED-mediated cyclopropane synthesis. [a] Using trans-b-methylstyrene. [b] Using cis-b-methylstyrene. [c] 20 equiv of styrene. [d] Violet LED used. Also 27% of malonate dimer by H NMR. 1[e] Using soluble ylide 1o.](http://www.wlxkc.cn/picture/5329828_16.png)
LED-mediated cyclopropane synthesis. [a] Using trans-b-methylstyrene. [b] Using cis-b-methylstyrene. [c] 20 equiv of styrene. [d] Violet LED used. Also 27% of malonate dimer by H NMR. 1[e] Using soluble ylide 1o.
CAS number: 7664-38-2
Phosphoric acid (H3PO4) is a colorless syrupy liquid. It is also known as orthophosphoric acid and its available analytical grade is 85%. Phosphoric acid is made from the mineral phosphorus, which is found naturally in many foods.
Concept of Dual Catalytic Gold and Organic Phosphoric Acid Enantioselective Cyclization Cascade
Chiral phosphoric acid catalysts.
![N,N-diallyl-p-toluenesulfonamide (5) was cycloisomerized in [D8]toluene (0.17 m) at 50 °C in the presence of B (5 mol%) and 2b (1 equiv). The relative contents of B, G and decomposition products were estimated by 31P NMR spectroscopy with H3PO4 (85%) as external standard and 1,2;5,6-dibenzanthracene (5 mol%) as internal standard.](http://www.wlxkc.cn/picture/1560075_38.png)
N,N-diallyl-p-toluenesulfonamide (5) was cycloisomerized in [D8]toluene (0.17 m) at 50 °C in the presence of B (5 mol%) and 2b (1 equiv). The relative contents of B, G and decomposition products were estimated by 31P NMR spectroscopy with H3PO4 (85%) as external standard and 1,2;5,6-dibenzanthracene (5 mol%) as internal standard.
BINOL-derived chiral phosphoric acid-catalyzed enantioselective B-V reaction of 3-substituted cyclobutanones
CAS number: 77-09-8
3,3-Bis(4-hydroxyphenyl)phthalide, also known as bisphenol A phthalide, is an organic compound characterized by its structure, which includes two hydroxyphenyl groups attached to a phthalide moiety. It is typically a white to off-white crystalline solid at room temperature.
Color development mechanism of phenolphthalein in alkaline solution
CAS number: 77-78-1
Dimethyl sulfate is a colorless oily liquid, odorless to a faint onion-like odor. It is very toxic by inhalation.
i) dimethyl sulfate, K2CO3, acetone, reflux; ii) NBS, AIBN, CCl4, reflux; iii) Br2, CHCl3, room temperature; iv) 1) Na2SO3·9H2O, ethanol, reflux; 2) Oxone, grade I alumina, CHCl3, reflux
CAS number: 77-95-2
Quinic acid is a cyclohexanecarboxylic acid contained in the extracts of several parts of medicinal plants including Haematocarpus validus, Hypericum empetrifolium, Achillea pseudoaleppica, Rumex nepalensis, Phagnalon saxatile subsp. saxatile, Coffea arabica, Ziziphus lotus L, and Artemisia annua L … etc.
Synthesis of (+)-9 from (−)-Quinic Acid
CAS number: 771-61-9
Pentafluorophenol is a highly fluorinated aromatic compound known for its unique properties and versatility in various applications.
Preparation of 2–5. a) pentafluorophenol, 1,3-diisopropylcarbodiimide, CH2Cl2; b) 2-phenylethylamine, 4-aminobutyric acid, or methylamine hydrochloride, iPr2EtN, DMF, 49% (13a), 70% (13b), or 68% (13c) yield for two steps; c) Ac2O, pyridine, then (for 4 and 6) H2O/dioxane, 99% (3), 81% (4), 90% (5), or 97% (6).
CAS number: 7758-99-8
Copper Sulfate Pentahydrate is the most common sulfate salt of copper. The blue, crystalline inorganic compound is a potent emetic used as an antidote for phosphorus poisoning.
Synthesis of nucleoside borane conjugates by “chemical ligation” of nucleoside borane acceptors and borane donors: 17–24. i) 2, 5, or 6, CuSO4·5H2O/potassium ascorbate, tert-butyl alcohol/water 1:1; ii) 7 or 8, CuSO4·5H2O/potassium ascorbate, tert-butyl alcohol/water 1:1
CAS number: 7789-20-0
Water-d₂, also known as heavy water, contains two deuterium atoms bonded to one oxygen atom. This substitution makes heavy water about 10% denser than normal water and alters some of its physical and chemical properties, such as a higher boiling point (101.4 °C) and melting point (3.8 °C). D₂O is primarily used as a neutron moderator in nuclear reactors, where it slows down neutrons without capturing them, enhancing the efficiency of nuclear fission. It is also utilized in certain analytical and spectroscopic techniques, including NMR, due to its unique nuclear properties.
1H NMR spectra following irradiation of 13 in D2O with λirr ≥ 395 nm for 0, 30, 60, and 120 min. Stars indicate new signals evolved upon irradiation.
Molecular characterization of homopolymers of 1 prepared by RAFT polymerization: (top) SEC chromatograms of different DPn samples recorded at 70 1C in DMSO; (bottom) H NMR spectrum of the homopolymer of 1 with an average chain length of 100 Å recorded in D2O.
Stability of 1c, 2c and 3c after Incubation in Deuterium Oxide at 37 °C for 48 h.