Chemicals list & Research Gallery

Porothramycin A
CAS number: 110652-73-8
Porothramycin A is a type of pyrrolobenzodiazepine (PBD) antibiotic, specifically a monomeric PBD. It is a natural product produced by actinomycetes, a group of bacteria known for producing various bioactive compounds.
Pyridinium ring-openings to form acyclic Zincke aldehydes, indoles, and dihydropyrroles relevant to the porothramycins. A ) activating group.
Pyridinium ring-openings to form acyclic Zincke aldehydes, indoles, and dihydropyrroles relevant to the porothramycins. A ) activating group.
Formal Syntheses of Porothramycins A and B
Formal Syntheses of Porothramycins A and B
Azepane
CAS number: 111-49-9
An azacycloalkane that is cycloheptane in which one of the carbon atoms is replaced by a nitrogen atom.
π-Stacking interaction favoring the azepane system.
π-Stacking interaction favoring the azepane system.
Octane
CAS number: 111-65-9
Octane is a gasoline additive that is needed for the proper functioning of modern engines.
IR spectra of the n-octane solution of 2 at 293 K and 353 K.
IR spectra of the n-octane solution of 2 at 293 K and 353 K.
UV-Vis-NIR spectra of the n-octane solution of 2 measured at 293 K (upper) and 353 K (lower). Solid red bars indicate the calculated transition of the 2opt (upper) and 3opt (lower).
UV-Vis-NIR spectra of the n-octane solution of 2 measured at 293 K (upper) and 353 K (lower). Solid red bars indicate the calculated transition of the 2opt (upper) and 3opt (lower).
1-Octene
CAS number: 111-66-0
1-octene appears as a colorless liquid. Flash point 70 °F. Insoluble in water and less dense (at about 6 lb / gal) than water. Hence floats on water. The alkene is classified as a higher olefin and alpha-olefin.
Phosphorus hydrides and the adducts from addition to 1-octene.
Phosphorus hydrides and the adducts from addition to 1-octene.
Order of reactivity of phosphorus hydrides to 1-octene.
Order of reactivity of phosphorus hydrides to 1-octene.
Heptanal
CAS number: 111-71-7
Heptanal is an n-alkanal resulting from the oxidation of the alcoholic hydroxy group of heptan-1-ol to the corresponding aldehyde.
Simplified scheme of the reaction of acetaldehyde and heptanal on a solid basic and acid catalyst.
Simplified scheme of the reaction of acetaldehyde and heptanal on a solid basic and acid catalyst.
Cross- and self-condensation from the carbanion of heptanal.
Cross- and self-condensation from the carbanion of heptanal.
Cross-condensation between the carbanion of acetaldehyde and heptanal.
Cross-condensation between the carbanion of acetaldehyde and heptanal.
Selectivity to 1 as a function of heptanal conversion in the reaction of acetaldehyde and heptanal at different reaction temperatures.
Selectivity to 1 as a function of heptanal conversion in the reaction of acetaldehyde and heptanal at different reaction temperatures.
Selectivity to 1 as a function of heptanal (A) and acetaldehyde (B) conversions in the reaction of acetaldehyde and heptanal at different acetaldehyde/heptanal molar ratios.
Selectivity to 1 as a function of heptanal (A) and acetaldehyde (B) conversions in the reaction of acetaldehyde and heptanal at different acetaldehyde/heptanal molar ratios.
DIF-1
CAS number: 111050-72-7
DIF-1 is a novel chlorinated alkyl phenone which induces differentiation of prestalk cells in Dictyostelium discoideum. DIF-1 is required for slug migration and specifies the anterior-like cells forming the basal disc and much of the lower cup.
Synthetic Routs to DIF Derivatives
Synthetic Routs to DIF Derivatives
Effects of DIF Derivatives on Cell Growth in HeLa, LM8, and 3T3-L1 Cells
Effects of DIF Derivatives on Cell Growth in HeLa, LM8, and 3T3-L1 Cells
Effects of DIF Derivatives on Infection and Growth of T. cruzi
Effects of DIF Derivatives on Infection and Growth of T. cruzi
Effects of DIF Derivatives on IL-2 Production in Jurkat T Cells
Effects of DIF Derivatives on IL-2 Production in Jurkat T Cells
Effects of DIF Derivatives on Glucose Consumption in 3T3-L1 Cells
Effects of DIF Derivatives on Glucose Consumption in 3T3-L1 Cells
Oxadiazoles
CAS number: 11120-54-0
An oxadiazole is defined as a doubly unsaturated 5-membered ring composed of two carbons, two nitrogens, and one oxygen atom. Oxadiazoles are a class of antibacterials discovered by in silico docking and scoring of compounds against the X-ray structure of a penicillin-binding protein.
Synthesis of oxadiazole from benzil dioxime.
Synthesis of oxadiazole from benzil dioxime.
N,N-Dimethylglycine
CAS number: 1118-68-9
N,N-dimethylglycine (DMG) is a naturally occurring compound being widely used as an oral supplement to improve growth and physical performance.
Schematic diagram showing the possible structural changes of BHMT during the binding process with substrates and products. The blue ovals (S1-S6) represent the different structural states of BMHT monomers. Hcy represents homocysteine, Bet represents betaine, Met represents methionine, Dmg represents dimethylglycine, and TS represents the assumed transition state of the substrate.
Schematic diagram showing the possible structural changes of BHMT during the binding process with substrates and products. The blue ovals (S1-S6) represent the different structural states of BMHT monomers. Hcy represents homocysteine, Bet represents betaine, Met represents methionine, Dmg represents dimethylglycine, and TS represents the assumed transition state of the substrate.
Oleic acid
CAS number: 112-80-1
Oleic acid is an octadec-9-enoic acid in which the double bond at C-9 has Z (cis) stereochemistry.
Oleic acid catalysed 4H-chromene synthesis.
Oleic acid catalysed 4H-chromene synthesis.
Oleic acid catalysed 4H-chromene synthesis by three-component reaction.
Oleic acid catalysed 4H-chromene synthesis by three-component reaction.
Oleic acid catalysed pyrimidine-fused heterocycles synthesis.
Oleic acid catalysed pyrimidine-fused heterocycles synthesis.
Oleic acid catalysed pyrimidine-fused heterocycles synthesis.
Oleic acid catalysed pyrimidine-fused heterocycles synthesis.
Oleic acid catalysed bioactive skeleton synthesis.
Oleic acid catalysed bioactive skeleton synthesis.
1,3-Cyclobutadiene
CAS number: 1120-53-2
1,3-Cyclobutadiene (C₄H₄) is a highly reactive and unstable organic compound that consists of a four-membered carbon ring with alternating single and double bonds, specifically at the 1 and 3 positions. Due to its antiaromatic nature — having 4 π-electrons in a conjugated planar system — it experiences significant electronic instability, which leads to rapid dimerization or reaction with other species under standard conditions. The molecule exists transiently in the gas phase or at very low temperatures and has a rectangular rather than square geometry, as predicted by molecular orbital theory to relieve some of the antiaromatic strain. 1,3-Cyclobutadiene is of considerable interest in theoretical and organometallic chemistry, particularly in studies of aromaticity, bonding, and as a ligand in metal complexes where its stability can be enhanced through coordination.
Calculated energies relative to the corresponding cyclobutadiene complex [34 + CO].
Calculated energies relative to the corresponding cyclobutadiene complex [34 + CO].