Chemicals list & Research Gallery

Aniline, acetate
CAS number: 542-14-3
Aniline acetate is a chemical compound formed by the reaction of aniline (an aromatic amine) with acetic acid. It typically appears as white crystalline solids and is used in organic chemistry as a reagent or intermediate. Aniline acetate combines the properties of both aniline—an oily, slightly yellow liquid with a characteristic odor—and acetate, contributing to its solubility in water and alcohol.
(A) Ligation of AOB to phage-displayed aldehydes is accelerated by aniline, but preincubation of phage with aniline in the absence of AOB leads to rapid loss of aldehyde and loss of reactivity toward AOB. (B) In anilinium acetate, pH 4.7, the aldehyde disappears with t1/2 ∼40 min; however, aldehydes alone are stable at the same pH in sodium acetate buffer.
(A) Ligation of AOB to phage-displayed aldehydes is accelerated by aniline, but preincubation of phage with aniline in the absence of AOB leads to rapid loss of aldehyde and loss of reactivity toward AOB. (B) In anilinium acetate, pH 4.7, the aldehyde disappears with t1/2 ∼40 min; however, aldehydes alone are stable at the same pH in sodium acetate buffer.
Fluoxetine
CAS number: 54910-89-3
Fluoxetine is a type of antidepressant known as a selective serotonin reuptake inhibitor (SSRI).
Structures of fluoxetine, atomoxetine, and nisoxetine.
Structures of fluoxetine, atomoxetine, and nisoxetine.
Examples of monoamine reuptake inhibitors containing a 3-aryl-3-phenoxypropylamine motif: fluoxetine, nisoxetine, atomoxetine
Examples of monoamine reuptake inhibitors containing a 3-aryl-3-phenoxypropylamine motif: fluoxetine, nisoxetine, atomoxetine
Farnesiferol B
CAS number: 54990-68-0
Farnesiferol B is a terpene lactone. ChEBI. Farnesiferol B has been reported in Ferula assa-foetida and Ferula gummosa with data available. LOTUS - the natural products occurrence database. See also: Ferula assa-foetida resin (part of).
Enantioselective Synthesis of (-)-Achilleol A and (+)-Farnesiferol B
Enantioselective Synthesis of (-)-Achilleol A and (+)-Farnesiferol B
Glycidol
CAS number: 556-52-5
Glycidol is an epoxide and an alcohol, and as such is a highly reactive compound. It is miscible with water but also reacts with it.
Synthesis of a Functionalized Glycidol Derivative
Synthesis of a Functionalized Glycidol Derivative
Carbon tetrabromide
CAS number: 558-13-4
Carbon tetrabromide, also known as tetrabromomethane, is a chemical compound with the formula CBr₄.
(A) The structure was optimized by DFT under vacuum conditions using the ωB97X-D function, 6-311G(d,p) for C,H, 6-311+G(d,p) for N,S, and Def2TZV for Br. (B) The electrostatic potentials of N-methylthioamide and tetrabromomethane were calculated on a 0.0004 au isodensity surface (ωB97X-D/Def2TZV) (red = negative electrostatic potential, blue = positive electrostatic potential).
(A) The structure was optimized by DFT under vacuum conditions using the ωB97X-D function, 6-311G(d,p) for C,H, 6-311+G(d,p) for N,S, and Def2TZV for Br. (B) The electrostatic potentials of N-methylthioamide and tetrabromomethane were calculated on a 0.0004 au isodensity surface (ωB97X-D/Def2TZV) (red = negative electrostatic potential, blue = positive electrostatic potential).
γ-Aminobutyric acid
CAS number: 56-12-2
Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter. It lessens a nerve cell's ability to receive, create or send chemical messages to other nerve cells.
Preparation of 2–5. a) pentafluorophenol, 1,3-diisopropylcarbodiimide, CH2Cl2; b) 2-phenylethylamine, 4-aminobutyric acid, or methylamine hydrochloride, iPr2EtN, DMF, 49% (13a), 70% (13b), or 68% (13c) yield for two steps; c) Ac2O, pyridine, then (for 4 and 6) H2O/dioxane, 99% (3), 81% (4), 90% (5), or 97% (6).
Preparation of 2–5. a) pentafluorophenol, 1,3-diisopropylcarbodiimide, CH2Cl2; b) 2-phenylethylamine, 4-aminobutyric acid, or methylamine hydrochloride, iPr2EtN, DMF, 49% (13a), 70% (13b), or 68% (13c) yield for two steps; c) Ac2O, pyridine, then (for 4 and 6) H2O/dioxane, 99% (3), 81% (4), 90% (5), or 97% (6).
Aspartimide
CAS number: 5615-80-5
Aspartimide is a byproduct formed during solid-phase peptide synthesis (SPPS) of aspartic acid-containing peptides.
Formation of aspartimides from β-peptide derivatives.
Formation of aspartimides from β-peptide derivatives.
1-Acetylaspidoalbidine
CAS number: 56197-21-8
1-Acetylaspidoalbidine is a member of carbazoles. It was first isolated from the plant Vallesia dichotoma. It is closely related to fendleridine (aspidoalbidine), with both compounds sharing a common core structure and being part of the aspidoalbine family.
Structures of (±)-1-acetylaspidoalbidine and (±)-1-methylaspidospermidine.
Structures of (±)-1-acetylaspidoalbidine and (±)-1-methylaspidospermidine.
The total synthesis of (±)-1-acetylaspidoalbidine and (±)-1-methylaspidospermidine.
The total synthesis of (±)-1-acetylaspidoalbidine and (±)-1-methylaspidospermidine.
Bropirimine
CAS number: 56741-95-8
Bropirimine is an oral immunostimulant that causes the body to produce interferon and other substances.
Bropirimine, a bioactive pyrimidinone.
Bropirimine, a bioactive pyrimidinone.
Cyanide
CAS number: 57-12-5
Cyanide is a rapidly acting, potentially deadly chemical that can exist as a gas, liquid, or solid (crystal).
The isocyanide cyclization range is 2a.
The isocyanide cyclization range is 2a.
Functionalized isocyanide complexes.
Functionalized isocyanide complexes.
Stereocontrolled Ugi Reaction with Keto Acid 12 and Convertible Isocyanide 8
Stereocontrolled Ugi Reaction with Keto Acid 12 and Convertible Isocyanide 8