Chemicals list & Research Gallery
CAS number: 1122-58-3
4-Dimethylaminopyridine is a dialkylarylamine and a tertiary amino compound. 4-Dimethylaminopyridine has been reported in Panax ginseng with data available.
A) Synthesis of acetonide and MTPA derivatives of mycalol (1). B) Δδ (δS-δR) values (ppm) for selected protons of (R)-MTPA ester 5 and (S)-MTPA ester 6. Reagents and conditions: a) (CD3)2CO, I2, RT, 24 h; b) (CH3)2C(OCH3)2, PPTS, 758C, 6 h; c) Na2CO3, MeOH, 558C, 28 h; d) S-(-)- or R-(-)-MTPA chloride, DMAP, dry CH2Cl2, RT, overnight. Ac=acetyl, DMAP=4-dimethylaminopyridine, MTPA-Mosher’s acid; a- methoxy-a-(trifluoromethyl)phenylacetic acid, PPTS-pyridinium p-toluenesulfonate
Synthesis of the BC ring system. DCC=dicyclohexylcarbo-diimide, DMAP=4-dimethylaminopyridine, DIBALH=diisobutylaluminum hydride, R=o-tolyl.
Preparation of cyclohexenol 16. DMAP=4-(dimethylamino)-pyridine, Cbz=benzyloxycarbonyl, THF=tetrahydrofuran, TBS=tert-butyldimethylsilyl, dppf=1,1'-bis(diphenylphosphino)ferrocene.
CAS number: 113411-17-9
DIF-3, or Differentiation-inducing factor 3, is a chlorinated hexaphenone compound derived from the cellular slime mold Dictyostelium discoideum. It's known for its role in cell differentiation and its potential as an anticancer agent. DIF-3 is structurally similar to DIF-1, another compound from the same family, and is involved in regulating various cellular processes.
Synthetic Routs to DIF Derivatives
Effects of DIF Derivatives on Cell Growth in HeLa, LM8, and 3T3-L1 Cells
Effects of DIF Derivatives on Infection and Growth of T. cruzi
Effects of DIF Derivatives on IL-2 Production in Jurkat T Cells
Effects of DIF Derivatives on Glucose Consumption in 3T3-L1 Cells
CAS number: 1148-79-4
2,2':6',2''-terpyridine is a tridentate heterocyclic ligand that binds metals at three meridional sites giving two adjacent 5-membered MN2C2 chelate rings.
Metal-binding conformation of the terdentate ligands (a) terpyridine (Terpy) and (b) 2,6-bisbenzimidazolylpyridine (Bip) with labeled functional sites: R, R0, X, and Y. The gray spheres represent metal ions.
CAS number: 117048-59-6
Combretastatin A-4 (CA-4) is a natural anti-cancer agent isolated in 1989 from the African willow tree, Combretum caffrum. A synthetic Combretum caffrum-derived cell-permeable stilbenoid phenol that competes with colchicine tubulin binding and interferes with tubulin polymerization.
Morphological effects of combretastatin A4 (CA-4) analogues. Endothelial cells (EAhy 926 cells) were exposed to the test compounds and incubated for 2 h at the indicated concentrations. Representative photographs were taken at a magnification of 360ꢂ.
CAS number: 118-10-5
Cinchonine is cinchonan in which a hydrogen at position 9 is substituted by hydroxy (S configuration). It occurs in the bark of most varieties of Cinchona shrubs, and is frequently used for directing chirality in asymmetric synthesis.
Aldol-Tishchenko Reaction in the Presence of Ti(OtBu)4/Cinchonine Complex
Possible mechanistic reaction pathway. Ti ) Ti(OtBu)4 or BINOLTi(OtBu)2/cinchonine.
CAS number: 1191-15-7
Diisobutylaluminum hydride (DIBAL-H) is an organometallic compound that has found wide use as a reducing agent.
Synthesis of the BC ring system. DCC=dicyclohexylcarbo-diimide, DMAP=4-dimethylaminopyridine, DIBALH=diisobutylaluminum hydride, R=o-tolyl.
CAS number: 1191-99-7
2,3-Dihydrofuran is defined as a five-membered aromatic heterocycle with an enthalpy of formation of −23.52 kcal mol −1, as calculated using semi-empirical methods.
A tunable tandem reaction towards the syntheses of dihydrofuran derivatives. SR=semipinacol rearrangement.
CAS number: 120-62-7
A sulfoxide is a chemical compound containing a sulfinyl group (S=O) bonded to two carbon atoms. It's essentially a sulfur atom with a double-bonded oxygen and two organic groups (R and R') attached. Sulfoxides are often derived from sulfides (R-S-R') through oxidation.
TFA/SBA-15 for green oxidation of sulfides to sulfoxides.
Reductive etherification reaction for the synthesis of sulfone 14 and sulfoxide 16.
CAS number: 120-75-2
2-Methylbenzothiazole is an organic chemical compound which is a benzothiazole derivative, meaning it contains a benzene ring fused to a thiazole ring.
![Scalability of the CBr4-catalyzed synthesis of 2-methylbenzo[d]thiazole.](http://www.wlxkc.cn/picture/1028122_84.png)
Scalability of the CBr4-catalyzed synthesis of 2-methylbenzo[d]thiazole.
CAS number: 120-93-4
2-Imidazolidinone is a cyclic urea compound with a five-membered ring containing two nitrogen atoms and a carbonyl group. It's used as a building block in synthesizing pharmaceuticals and agrochemicals, and as a formaldehyde scavenger in various industries. It also has applications in detergents, dyestuffs, and electronic materials.
Preparation of the monolithic reactor containing the chiral imidazolidinone catalyst Supp-3.
Enantioselective Diels–Alder reactions with different substrates under continuous-flow conditions catalyzed by imidazolidinone supported catalyst Supp-3.
Enantioselective catalytic reactions under continuous-flow conditions with imidazolidinone supported catalyst Supp-3.