Chemicals list & Research Gallery
CAS number: 67-68-5
Dimethyl sulfoxide is a 2-carbon sulfoxide in which the sulfur atom has two methyl substituents. It has a role as a polar aprotic solvent, a radical scavenger, a non-narcotic analgesic, an antidote, a MRI contrast agent, an Escherichia coli metabolite, a geroprotector and an alkylating agent. It is a sulfoxide and a volatile organic compound.
Chemical transformations. DmS=dimethylsulfoxide, NBS=N-bromosuccinimide, NIS=N-iodosuccinimide, PPA=poly-phosphoric acid.
CAS number: 672-155-8
5-Amino-1,2,4-thiadiazole is a nitrogen and sulfur-containing heterocyclic organic compound that is known to be harmful if swallowed and can cause skin, eye, and respiratory irritation. It is sometimes found as an intermediate in the synthesis of other chemical compounds.
Synthesis of hydroxamic acids derived from 2-L-aminosuberic acid.
Substrate Scope of 5-Amino-1,2,4-thiadiazole Synthesis
CAS number: 67254-79-9
Fatty acids, one class of essential nutrients for humans, are an important source of energy and an essential component of cell membranes. Most fatty acids in plants and animals have an even carbon number and no branching. One or more double bonds may occur, mostly in cis configuration. More than 40 different fatty acids are commonly encountered in foods.
N-Substituted pantothenamides (such as N-pentyl pan- tothenamide shown above) act as antimetabolites by forming coenzyme A analogues which do not contain the essential terminal thiol group of natural CoA. These analogues subsequently transfer inactive prosthetic groups to the acyl carrier proteins that are involved in fatty acid metabolism, thereby blocking these processes.
CAS number: 67262-86-6
Tn Antigen is a protein antigen that is comprised of the monosaccharide N-acetylgalactosamine (GalNAc) bound to serine or threonine by O-linked glycosylation. Aberrant expression of Tn antigen by all blood cell lineages is associated with a rare hematological disorder called Tn-syndrome.
Structures of the TN- and the T-antigen.
Synthesis of a TN-Antigen Building Block
CAS number: 675-20-7
Piperidin-2-one is a delta-lactam that is piperidine which is substituted by an oxo group at position 2. It has a role as an EC 1.2.1.88 (L-glutamate gamma-semialdehyde dehydrogenase) inhibitor. It is a member of piperidones and a delta-lactam.
Proposed explanation of the diastereoselective formation of 2-pyrrolidinones 7 and 2-piperidinones 8.
Synthesis of a 768-membered library of 2-piperidinones fused to dihydropyrans.
CAS number: 6780-38-7
2H-Isoindole-2-acetyl chloride, 1,3-dihydro-1,3-dioxo- is an organic chemical compound, specifically a derivative of isoindole. It is characterized by the presence of an acetyl chloride group attached to the nitrogen atom of a 2H-isoindole-1,3-dione moiety.
Synthesis of N-alkoxy-N-alkyl diazoamides 4a–4l: a) Phthalylglycyl chloride, Et3N, CH2Cl2, 0℃, 5 h; b) hydrazine, ethanol, 40℃, 4 h; then NaNO2, H2O, CH2Cl2, HCl or HOAc (pH 2–4), 0℃, 2 h.
CAS number: 68-12-2
N,N-dimethylformamide is a member of the class of formamides that is formamide in which the amino hydrogens are replaced by methyl groups. It has a role as a polar aprotic solvent, a hepatotoxic agent and a geroprotector. It is a volatile organic compound and a member of formamides. It is functionally related to a formamide.
Representative normalized absorption (solid) and fluorescence spectra (dotted) (kexc = 550 nm, OD = 0.02) of flavonoid–porphyrin conjugate 17 in DMF.
CAS number: 68-89-3
Dipyrone, also known as metamizole, is a pain reliever (analgesic) and fever reducer (antipyretic) that is used to treat moderate to severe pain and fever. It is available in various forms like oral tablets, suppositories, and injections. While widely used in many countries, it has been banned or restricted in some, including the United States, due to concerns about potentially serious side effects like agranulocytosis (a severe reduction in white blood cells).
Metabolites of dipyrone (1).
Concentrations of 5 (A) and 6 (B) in the brain of wild-type mice (FAAH+/+) and of FAAH knockout mice (FAAHÀ/À) after administration of dipyrone or water for five days (n = 3 mice/group, mean SEM).
CAS number: 682741-29-3
HTS 01037 is a ring assembly and a member of thiophenes.
Structure of BMS309403, HTS01037, 1 and 12b.
CAS number: 6829-55-6
(R)-3,4-Dihydro-2-methyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-2H-1-benzopyran-6-ol is a diterpenoid.
Structure of chromane, vitamin E (tocopherols and tocotrienols