Chemicals list & Research Gallery

1,2,4-triazole-3-carboxamide is a member of the class of triazoles that is 1H-1,2,4-triazole substituted by an aminocarbonyl group at position 3. It is the major catabolite and aglycon of ribavirin. It has a role as a human urinary metabolite and a drug metabolite. It is a member of triazoles, a primary carboxamide, a monocarboxylic acid amide and an aromatic amide.

3-Amino-2,3,6-trideoxy-3-C-methyl-L-lyxo-hexose is a branched-chain amino sugar also known as L-vancosamine. It's a key component of the antibiotic vancomycin and other related antibiotics. Specifically, it's found as a sugar component in the glycopeptide antibiotic vancomycin, which is important in treating methicillin-resistant Staphylococcus aureus. It also appears in other antibiotic structures as an O-glycoside or a C-glycoside.

2,2'-Bipyridine, also known as bipy or bpy, is a symmetrical bipyridine, meaning it has two pyridine rings connected at the 2 and 2' positions. It's a versatile bidentate ligand in coordination chemistry, forming stable complexes with various metal ions.

Verapamil is a calcium channel blocker that widens your blood vessels and relaxes your heart muscle.

Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. However there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food. FDA approved on July 1, 2011.

Ribavirin is a 1-ribosyltriazole that is the 1-ribofuranosyl derivative of 1,2,4-triazole-3-carboxamide. A synthetic guanosine analogue, it is an inhibitor of HCV polymerase and possesses a broad spectrum of activity against DNA and RNA viruses.

Levoglucosenone (LGO) is a chiral, bio-based molecule produced from the pyrolysis of cellulose and other biomass materials.

Triflate is an organosulfonate oxoanion resulting from the removal of a proton from the sulfonic acid group of triflic acid. It is a conjugate base of a triflic acid.

Quinocycline A, also known as PA-371-A''1, is a quinocycline-class natural product derived from Streptomyces species, characterized by a tetracyclic core with a unique quinoline moiety. It exhibits potent antibacterial activity, particularly against Gram-positive bacteria, including Staphylococcus aureus and drug-resistant strains such as MRSA. Structurally, it combines features of both tetracyclines and quinolines, contributing to its mechanism of action, which is believed to involve inhibition of bacterial protein synthesis. Quinocycline A is of interest in antibiotic discovery for its novel scaffold and promising bioactivity, offering a potential lead compound for addressing antibiotic resistance.

Quinocycline B, also known as PA-371-D'', is a synthetic tetracycline derivative with broad-spectrum antibacterial and potential anticancer properties. It was originally developed for its antimicrobial activity but has since attracted interest for its ability to inhibit tumor cell growth, particularly in drug-resistant cancer cells. Quinocycline B functions by targeting mitochondrial function and inducing apoptosis through pathways independent of p53, making it a promising candidate for overcoming resistance mechanisms in cancer therapy.