Ribavirin is a 1-ribosyltriazole that is the 1-ribofuranosyl derivative of 1,2,4-triazole-3-carboxamide. A synthetic guanosine analogue, it is an inhibitor of HCV polymerase and possesses a broad spectrum of activity against DNA and RNA viruses.
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Examples of some bioactive compounds containing 1,2,4-triazole moiety.
IMP dehydrogenase activity measurements in L1210 and CEM cell cultures in the presence of ribavirin and the test compounds.
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