Serine is an alpha-amino acid that is alanine substituted at position 3 by a hydroxy group. It has a role as a fundamental metabolite. It is an alpha-amino acid and a polar amino acid. It contains a hydroxymethyl group. It is a conjugate base of a serinium. It is a conjugate acid of a serinate. It is a tautomer of a serine zwitterion.
Structures and function of the target molecules of this study. (A) General structures of the two types of heterocycles created here. (B) Structures of two 1,3,4-oxadiazol-2-ones reported to be inhibitors of serine hydrolases.
5-Nitroimidazole is a nitrogen heterocyclic compound that is a key component in the development of various drugs with antimicrobial, antiparasitic, and antiviral properties.
Zidovudine is a pyrimidine 2',3'-dideoxyribonucleoside compound having a 3'-azido substituent and thymine as the nucleobase. It has a role as an antiviral drug, an antimetabolite and a HIV-1 reverse transcriptase inhibitor. It is a pyrimidine 2',3'-dideoxyribonucleoside and an azide.
Several Pharmacologically Useful Agents Containing Uracil and Piperazine Moieties: 5-Fluorouracil, Uramustine, Methylthiouracil, stavudine, zidovudine, prazosin, trazodone, Fluanisone, urapidil.
Tubulysin D is a highly cytotoxic anti-microtubule toxin (anti-microtubule toxins) that is synthesized as an ADC cytotoxin (ADC Cytotoxin). Tubulysin D can be isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis.
N-Phenylindole, also known as 1-Phenyl-1H-indole, is an aromatic organic compound composed of an indole core with a phenyl group attached at the nitrogen atom (N1 position).
Regioselective Electrophilic Palladation at the C3 Position of N-Phenylindole
Crystal structures of 7−10 and the possible pathway to 10 through C3 palladation of N-phenylindole (L1 = OAc, L2 = PivO, L3 = MeO−).
pH-Dependent Highly Regioselective Electrophilic Palladation at the C2 or C3 Position of N-Methylindole and X-ray Crystal Structures of Compounds 12 and 13
Cyanoboron, or more precisely sodium cyanoborohydride (NaCNBH3), is a chemical compound primarily used as a reducing agent in organic synthesis. It's known for being a milder reducing agent than sodium borohydride (NaBH4) and is particularly useful for selectively reducing imines to amines in the presence of other carbonyl compounds like ketones and aldehydes.
Synthesis of diisopropylamine-cyanoborane 1 and diisopropylamino-(cyano)borane 2.
Mebendazole is a carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5. It has a role as an antinematodal drug, a tubulin modulator and a microtubule-destabilising agent. It is a member of benzimidazoles, a carbamate ester and an aromatic ketone. It derives from a hydride of a 1H-benzimidazole.
Complete dissociation of mebendazole (MBZ) ligand from the original framework of complex 1 in DMSO.
(S)-camphorsulfonic acid is the S enantiomer of camphorsulfonic acid. It is a conjugate acid of a (S)-camphorsulfonate. It is an enantiomer of a (R)-camphorsulfonic acid.