Chemicals list & Research Gallery

3-Cyano-2-pyridone
CAS number: 20577-27-9
3-cyano-2-pyridone is a member of pyridines and a nitrile.
Synthesis of 3-Cyano-2-pyridones from 4-Substituted Chalcones and Cyanoacetamide.
Synthesis of 3-Cyano-2-pyridones from 4-Substituted Chalcones and Cyanoacetamide.
Two-Step Synthesis of 1,3-Diketones 3 from 3-Cyano-2-pyridones 1-K.
Two-Step Synthesis of 1,3-Diketones 3 from 3-Cyano-2-pyridones 1-K.
trans-Isochavicol
CAS number: 20649-39-2
Trans-anol is a phenylpropanoid that is phenol substituted at position 4 by a prop-1-enyl group (the trans-isomer) It is a phenylpropanoid and a member of phenols. It is functionally related to a phenol.
Structures of isochavicol (1) and of constituents 2-4 of D. crinitus essential oil.
Structures of isochavicol (1) and of constituents 2-4 of D. crinitus essential oil.
2-Methyl-5-phenyl-2H-tetrazole
CAS number: 20743-49-1
2-Methyl-5-phenyl-2H-tetrazole is a chemical compound characterized by a five-membered heterocyclic ring (tetrazole) with a methyl group and a phenyl group attached to it.
Photolysis of 2-Methyl-5-phenyltetrazole 16
Photolysis of 2-Methyl-5-phenyltetrazole 16
IR difference spectrum obtained after 254 nm photolysis of 2-methyl-5-phenyltetrazole 16 in Ar matrix at 12 K. Negative peaks: starting material. Positive peaks: product formed.
IR difference spectrum obtained after 254 nm photolysis of 2-methyl-5-phenyltetrazole 16 in Ar matrix at 12 K. Negative peaks: starting material. Positive peaks: product formed.
Daunorubicin
CAS number: 20830-81-3
Daunorubicin is a natural product found in Actinomadura roseola. It has a role as an antineoplastic agent and a bacterial metabolite. It is an anthracycline, a member of tetracenequinones, a member of p-quinones and an aminoglycoside antibiotic. It is a conjugate base of a daunorubicin(1+). It derives from a hydride of a tetracene.
Structures of L-daunosamine 1, L-3-epi-daunosamine 2, L-ristosamine 3, L-acosamine 4, and the anthracycline antibiotics daunorubicin 5, doxorubicin 6, carubicin 7, idarubicin 8, and epirubicin 9.
Structures of L-daunosamine 1, L-3-epi-daunosamine 2, L-ristosamine 3, L-acosamine 4, and the anthracycline antibiotics daunorubicin 5, doxorubicin 6, carubicin 7, idarubicin 8, and epirubicin 9.
L-tert-Leucine
CAS number: 20859-02-3
L-tert-Leucine is an unnatural, non-polar amino acid with a tert-butyl group. It's known for its hydrophobicity and steric hindrance, which makes it useful in synthesizing chiral compounds. It's used in various applications, including the synthesis of pharmaceuticals, as a food additive, and in cosmetic formulations.
Synthesis of l-tert-leucine via reductive amination.
Synthesis of l-tert-leucine via reductive amination.
Berberine
CAS number: 2086-83-1
Berberine is a compound extracted from several plants. It has many health benefits and may help protect against several chronic conditions.
Structure of berberine derivatives
Structure of berberine derivatives
Corilagin
CAS number: 2088321-44-0
Corilagin is an ellagitannin with a hexahydroxydiphenoyl group bridging over the 3-O and 6-O of the glucose core. It has a role as an antihypertensive agent, an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, a non-steroidal anti-inflammatory drug and an antioxidant. It is an ellagitannin and a gallate ester.
Structure of corilagin (1).
Structure of corilagin (1).
SB-271046
CAS number: 209481-20-9
5-chloro-N-(4-methoxy-3-(piperazin-1-yl)phenyl)-3-methylbenzo[b]thiophene-2-sulfonamide is a chemical compound, specifically a potent and selective 5-HT6 receptor antagonist. It is also known as SB-271046.
Pharmaceuticals containing the benzo[b]thiophene core structure: raloxifene, arzoxifene, zileuton, SB-271046, sertaconazole
Pharmaceuticals containing the benzo[b]thiophene core structure: raloxifene, arzoxifene, zileuton, SB-271046, sertaconazole
MS 275
CAS number: 209783-80-2
Entinostat, also known as MS 275, is a synthetic benzamide derivative with potential antineoplastic activity. Entinostat binds to and inhibits histone deacetylase, an enzyme that regulates chromatin structure and gene transcription. This agent appears to exert dose-dependent effects in human leukemia cells including cyclin-dependent kinase inhibitor 1A (p21/CIP1/WAF1)-dependent growth arrest and differentiation at low drug concentrations; a marked induction of reactive oxygen species (ROS); mitochondrial damage; caspase activation; and, at higher concentrations, apoptosis. In normal cells, cyclin-dependent kinase inhibitor 1A expression has been associated with cell-cycle exit and differentiation.
ZOLINZA®, Biaryl 1, MS-275, and SHI-1:2 2a.
ZOLINZA®, Biaryl 1, MS-275, and SHI-1:2 2a.
HDAC selectivity of Zolinza®, 1, MS-275, and SHI-1:2 2a
HDAC selectivity of Zolinza®, 1, MS-275, and SHI-1:2 2a
4-Pentenal
CAS number: 2100-17-6
4-Pentenal is an aldehyde.
Rhodium-catalyzed isomerization of 4-pentenals into 3-pentenals by endocyclic b-H elimination.
Rhodium-catalyzed isomerization of 4-pentenals into 3-pentenals by endocyclic b-H elimination.
Scope of the chemo- and stereoselective isomerization of 4-pentenals into (E)-3-pentenals. All of the yields are given for isolated products as the average of two experiments; see the Supporting Information. [a] Yield determined by 1H NMR spectroscopy in [D6]acetone in the presence of an internal standard. [b] Room temperature.
Scope of the chemo- and stereoselective isomerization of 4-pentenals into (E)-3-pentenals. All of the yields are given for isolated products as the average of two experiments; see the Supporting Information. [a] Yield determined by 1H NMR spectroscopy in [D6]acetone in the presence of an internal standard. [b] Room temperature.