Chemicals list & Research Gallery
CAS number: 53-84-9
NAD zwitterion is a NAD. It has a role as a geroprotector. It is functionally related to a deamido-NAD zwitterion. It is a conjugate base of a NAD(+).
TR is a prodrug that requires metabolic activation into its active form, tiazofurin adenine dinucleotide (TAD, Figure 1), a mimic of nicotinamide adenine dinucleotide (NAD).
CAS number: 530-26-7
D-mannopyranose is d-Mannose in its six-membered ring form. It has a role as a metabolite. It is a D-aldohexose, a D-mannose and a mannopyranose.
Chemical structures of mannose-substituted tetraphenylethylenes (TPEs), 1a–c.
CAS number: 530-53-0
Deoxyvasicinone is a member of quinazolines.
Total ion chromatogram and extracted mass chromatograms obtained from an incubation mixture with Desoxypeganine 1. Peak 1 Vasicinone 3, Peak 2 Isovasicinone 4, Peak 3 Pegenone 2.
Lineweaver-Burk plot of C-oxidation of Desoxypeganine 1 measured by Pegenone 2 formation in the incubation mixtures containing the components described under Materials and methods. Mean values are presented from three determinations.
CAS number: 5302-27-2
A-10749, known as 1,2-Diisopropyl urazole, is useful in organic synthesis, particularly in the formation of nitrogen-containing heterocycles or as a building block in medicinal chemistry. Its molecular formula reflects the presence of eight carbons, fifteen hydrogens, three nitrogens, and two oxygens, contributing to its chemical reactivity and potential applications.
Examples of non-imidazole-derived H3 antagonists: Aplysamine-1, UCL-1972, Abbott(A-10749).
CAS number: 531-59-9
Herniarin is a member of the class of coumarins that is coumarin substituted by a methoxy group at position 7. It has a role as a fluorochrome.
Specific monitoring of chymotrypsin activity in a dual substrate peptide. Incubation of a thioamide/7-methoxycoumarin labeled peptide with both chymotrypsin and trypsin cleavage sites results in a gain of fluorescence only in the presence of chymotrypsin.
CAS number: 53179-07-0
Nisoxetine was first developed by Eli Lilly as a non-tricyclic antidepressant drug.
Structures of fluoxetine, atomoxetine, and nisoxetine.
Examples of monoamine reuptake inhibitors containing a 3-aryl-3-phenoxypropylamine motif: fluoxetine, nisoxetine, atomoxetine
CAS number: 532-34-3
Butopyronoxyl is a member of pyrans and a carbonyl compound.
Construction of the spiroacetal dihydropyrone 17.
CAS number: 53230-10-7
Malaria is a protozoan disease that places an enormous burden on human health in endemic areas around the world. The 2020 World Health Organization malaria report indicates a 60% decrease in the global malaria fatality rate between 2000 to 2019. Despite this, malaria remains a significant cause of morbidity and mortality; 90% of deaths from malaria occur in Africa. Individuals at the highest risk for malaria are those in disease naïve populations, children under age 5, refugees in Central and Eastern Africa, nonimmune civilian and military travelers, pregnant women, and immigrants traveling to their place of origin.
IC50 data against Cambodia–Thai patient isolates for 15 compared with other antimalarials. Blue: mefloquine; red: artesunate; green: artemisinin; purple: RKA182.
CAS number: 5326-23-8
6-Chloronicotinic acid, also known as 6-chloropyridine-3-carboxylic acid, is a pyridine derivative, specifically a pyridinecarboxylic acid, and is characterized by a chlorine atom at the 6th position and a carboxylic acid group at the 3rd position of the pyridine ring. It is a white to beige crystalline powder.
Potential Products in Reaction between 6-Chloronicotinic Acid Derivatives and Homopiperazine
CAS number: 5328-64-3
D-Glycero-D-galacto-heptose is a seven-carbon sugar, specifically a heptose, that is a crucial component of bacterial lipopolysaccharides and plays a role in their structure and function. It's also a valuable chemical intermediate used in the synthesis of various bioactive molecules and has potential medicinal properties.
Preparation of Heptoses 5 and 6
Preparation of Heptoses 39 and 40
Preparation of Heptoses 50 and 51