Sedoheptulose 7-phosphate is a ketoheptose phosphate consisting of sedoheptulose having a phosphate group at the 7-position. It is an intermediate metabolite in the pentose phosphate pathway. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a sedoheptulose derivative and a ketoheptose phosphate. It is functionally related to a sedoheptulose. It is a conjugate acid of a sedoheptulose 7-phosphate(2-).
Xanthatin is a sesquiterpene lactone. Xanthatin, a sesquiterpene lactone purified from Xanthium strumarium L., possesses a significant antitumor role in several malignant tumors.
Retrosynthetic analysis of xanthatin.
Synthesis of the bicyclic core structure 2 of xanthatin.
Final steps in the synthesis of xanthatin 1a and side-chain analogues 1b–c.
Etravirine is an aminopyrimidine that consists of 2,6-diaminopyrimidine bearing a bromo substituent at position 5, a 4-cyano-2,6-dimethylphenoxy substituent at position 4 and having a 4-cyanophenyl substituent attached to the 2-amino group. NNRTI of HIV-1, binds directly to RT and blocks RNA-dependent and DNA-dependent DNA polymerase activities It has a role as a HIV-1 reverse transcriptase inhibitor and an antiviral agent. It is a dinitrile, an organobromine compound, an aminopyrimidine and an aromatic ether.
Chemical structures of DAPY, DATA and target compounds.
2,3-Benzofuran is a colorless, sweet-smelling, oily liquid made by processing coal into coal oil. It may also be formed during other uses of coal or oil. 2,3-Benzofuran is not used for any commercial purposes, but the part of the coal oil that contains 2,3-benzofuran is made into a plastic called coumarone-indene resin.
Strategies for the synthesis of indoles and benzofurans.
1H-Pyrazolo[4,3-b]pyridine is a specific chemical structure, a fused aromatic heterocyclic compound, that is significant in medicinal chemistry and materials science. It serves as a core component or scaffold in the development of various pharmaceuticals, including drugs for cancer, neurological disorders, and inflammation. Due to its unique structural and electronic properties, it is also investigated for use in advanced materials, such as organic semiconductors and sensors.
Pyrazolopyridine and 4-(pyrazol-4-yl)pyrimidines inhibitors.
Imidazo[4,5-b]pyridine is a heterocyclic compound consisting of a pyridine ring fused with an imidazole ring at the 4,5 positions. It's a molecule of interest in medicinal chemistry due to its structural similarity to purines and its diverse biological activities.
Concept: 2- and 6-trifluoromethyl-containing purines and 1-deazapurines as inhibitors of adenosine deaminase (ADA).
2-(6-methoxynaphthalen-2-yl)prop-2-enoic acid, also known as Dehydronaproxen, is an intermediate used in the quality control and commercial production of Naproxen, an anti-inflammatory drug. Dehydronaproxen is a close chemical relative of Naproxen, differing by the presence of an extra double bond in the propanoic acid group.
Ru(R-P-phos)-catalyzed Asymmetric Hydrogenation of 2-(6'-Methoxy-2'-naphthyl)propenoic Acid