Chemicals list & Research Gallery

Methoxydimethylphenylsilane, also known as Silane, methoxydimethylphenyl-, is an organosilicon compound featuring a phenyl group (C6H5) attached to a silicon atom, which is also bonded to two methyl groups (CH3) and a methoxy group (OCH3). This colorless to pale yellow liquid is used as a reagent in organic synthesis and materials science, particularly in surface modification, silane coupling applications, and as a precursor in the production of silicones or functionalized silanes. Its structure allows for reactivity with hydroxyl groups, making it useful in adhesion promotion, coatings, and polymer cross-linking.

Bortezomib is l-Phenylalaninamide substituted at the amide nitrogen by a 1-(dihydroxyboranyl)-3-methylbutyl group and at N(alpha) by a pyrazin-2-ylcarbonyl group. Bortezomib was first synthesized in 1995. In May 2003, bortezomib became the first anticancer proteasome inhibitor that was approved by the FDA under the trade name VELCADE. Phase I, II, III, and IV clinical trials are undergoing to investigate the therapeutic efficacy of bortezomib in leukemia, myasthenia gravis, systemic lupus erythematosus, rheumatoid arthritis, and solid tumours.

3-Tolylboronic acid is a boronic acid derivative, specifically featuring a methyl group attached to the third carbon of a phenyl ring, which is further linked to a boronic acid group. This compound is a white solid and is primarily used as a reagent in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions.

Tryprostatin B is a cyclic dipeptide that is brevianamide F (cyclo-L-Trp-L-Pro) substituted at position 2 on the indole ring by a prenyl group. It is a dipeptide, a member of indoles, a pyrrolopyrazine and an indole alkaloid. It is functionally related to a brevianamide F.

5-Phenyl-1H-tetrazole is a heterocyclic compound characterized by a phenyl group attached to a tetrazole ring. It's a white to light beige powder.

2'-alpha-mannosyl-L-tryptophan is a C-glycosyl compound that is L-tryptophan in which the hydrogen at position 2 on the indole protion has been replaced by an alpha-mannosyl residue. It is a L-tryptophan derivative and a C-glycosyl compound. It is functionally related to an alpha-D-mannose. It is a tautomer of a 2'-alpha-mannosyl-L-tryptophan zwitterion.

Sulfonium is a sulfur hydride, a sulfonium compound and an onium cation. It is a conjugate acid of a hydrogen sulfide.

Valdecoxib is a sulfonamide derivative and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities. Valdecoxib selectively binds to and inhibits cyclooxygenase (COX)-2, thereby preventing the conversion of arachidonic acid into prostaglandins, which are involved in the regulation of pain, inflammation, and fever. This NSAID does not inhibit COX-1 at therapeutic concentrations and therefore does not interfere with blood coagulation.

(-)-beta-pinene is the (1S,5S)-enantiomer of beta-pinene. It is an enantiomer of a (+)-beta-pinene.

Arzoxifene is a synthetic, aromatic derivative with anti-estrogenic properties. Similar to the agent raloxifene, arzoxifene binds to and interacts with estrogen receptors as a mixed estrogen agonist/antagonist. This agent exhibits greater bioavailability and higher anti-estrogenic potency in the breast than does raloxifene; it exhibits reduced estrogenicity in the uterus compared with either tamoxifen or raloxifene. Arzoxifene may have beneficial effects on bone and the cardiovascular system (NCI04)