1H-tetrazole is a tetrazole tautomer where the proton is located on the 1st position. It is a tetrazole and a one-carbon compound. It is a tautomer of a 2H-tetrazole and a 5H-tetrazole.
IR difference spectrum after 1 min photolysis (254 nm) of 5-phenyltetrazole 2 in Ar matrix at 12 K. Positive peaks: photolysis products, largely benzonitrile imine 6; the peak near 1700 cm−1 is due to an impurity on the deposition window. Negative peaks: reacted tetrazole 2.
1,3,4-Oxadiazole is a five-membered heterocyclic aromatic compound containing one oxygen atom and two nitrogen atoms, positioned at the 1, 3, and 4 positions. It's a key structural motif in many biologically active molecules and is known for its diverse pharmacological properties.
The preparation of a representative small series of 1,3,4-oxadiazoles containing the 6-phenoxy-1,2,3,4-tetrahydronaphthalene side chain was conducted.
1,2,4,5-Tetroxane is a cyclic organic peroxide with a four-membered ring containing two oxygen-oxygen (peroxide) bonds. It's a class of compounds known for their antimalarial activity and has been the subject of research for potential use as a drug.
Tetraoxane candidate development:[13] SAR trends of novel 1,2,4,5-tetraoxanes and candidate selection of RKA182.
Silver triflate is a highly effective catalyst in organic reactions, promoting reactions like Friedel-Crafts reactions, nucleophile-alkene cyclizations, and esterifications. Silver triflate can be prepared from the reaction of trifluoromethanesulfonic acid with silver oxide or silver carbonate.
Scope Investigation for the Silver Triflate-Catalyzed Tandem Reaction of 2-Alkynylbenzaldoxime 1 with Alkylide-necyclopropane 2
Possible Mechanism for the Silver Triflate-Catalyzed Tandem Reaction of 2-Alkynylbenzaldoxime 1 with Alkylide-necyclopropane 2
2-Cyclopropen-1-one is a highly strained, three-membered cyclic ketone. As the smallest member of the cyclopropenone family, it consists of a cyclopropene ring bearing a carbonyl group, making it both aromatic and electrophilic.
Photochemical decarbonylation of a cyclopropenone caged BCN probe (photo-DMBO) activates reactivity toward tetrazine-containing proteins, conferring spatial and temporal control over protein labeling.
3-Pyridinyl is a substituted pyridine ring in which a functional group is attached at the third carbon of the six-membered aromatic nitrogen-containing ring. The parent structure, pyridine, is similar to benzene but contains one nitrogen atom replacing a CH group, imparting basicity and unique reactivity. In the 3-pyridinyl configuration (also called meta-pyridyl), the substituent is bonded to the carbon atom adjacent to the nitrogen (but not directly next to it), influencing the molecule's electronic and steric properties. This moiety is commonly found in pharmaceuticals, agrochemicals, and ligands due to its ability to participate in hydrogen bonding, coordination chemistry, and π–π interactions.