Chemicals list & Research Gallery

meta-Topolin
CAS number: 75737-38-1
Meta-topolin (mT) is a relatively new cytokinin isolated from poplar leaves in 1975 and is closely related to 6-benzyladenine (BA).
Comparison of the perception of THP and THF substituted 6-(3-hydroxybenzylamino)purine (meta-topolin, mT) and mT by selected cytokinin receptors. The effect of 6-(3-hydroxybenzylamino)-9-tetrahydropyran-2-ylpurine (6(3OHBA)9THPP) and 6-(3-hydroxybenzylamino)-9-tetrahydrofuran-2-ylpurine (6(3OHBA)9THFP) on the sensing of mT by the cytokinin receptors CRE1/AHK4 (A) and AHK3 (B). trans-Zeatin (tZ) was used as the positive control.
Comparison of the perception of THP and THF substituted 6-(3-hydroxybenzylamino)purine (meta-topolin, mT) and mT by selected cytokinin receptors. The effect of 6-(3-hydroxybenzylamino)-9-tetrahydropyran-2-ylpurine (6(3OHBA)9THPP) and 6-(3-hydroxybenzylamino)-9-tetrahydrofuran-2-ylpurine (6(3OHBA)9THFP) on the sensing of mT by the cytokinin receptors CRE1/AHK4 (A) and AHK3 (B). trans-Zeatin (tZ) was used as the positive control.
beta-Cyclodextrin
CAS number: 7585-39-9
Beta-cyclodextrin is a cyclodextrin composed of seven alpha-(1->4) linked D-glucopyranose units.
Benzylated β-cyclodextrin-aldehyde and its reaction with organometallic reagents. This leads to two stereoisomers with rather different polarity.
Benzylated β-cyclodextrin-aldehyde and its reaction with organometallic reagents. This leads to two stereoisomers with rather different polarity.
TLC plate showing the different polarities of diastereoisomers 6A,D-di-C-allyl-substituted nonadecaned-O-benzylated β-cyclodextrin in pentane/ethyl acetate 4:1 eluent (left). The figure shows how steric hindrance of the subsequent glucose residue prevents the C-6 substituent from entering the tg conformation, thus forcing each diastereomer to adopt the conformer shown (right).
TLC plate showing the different polarities of diastereoisomers 6A,D-di-C-allyl-substituted nonadecaned-O-benzylated β-cyclodextrin in pentane/ethyl acetate 4:1 eluent (left). The figure shows how steric hindrance of the subsequent glucose residue prevents the C-6 substituent from entering the tg conformation, thus forcing each diastereomer to adopt the conformer shown (right).
Two reference monosaccharide derivatives 5a and 5b were prepared to determine the stereochemistry at the C-6 position. The major isomer 5b obtained by addition of (4-fluorophenyl)magnesium bromide to glucose-6-aldehyde 4 was converted to the benzylidene derivative 6. This compound has a small J5,6 and only conforms to the S-stereochemistry. The β-cyclodextrin derivative 2f was hydrolyzed and converted to the methyl glycoside to give the minor R-isomer 5a.
Two reference monosaccharide derivatives 5a and 5b were prepared to determine the stereochemistry at the C-6 position. The major isomer 5b obtained by addition of (4-fluorophenyl)magnesium bromide to glucose-6-aldehyde 4 was converted to the benzylidene derivative 6. This compound has a small J5,6 and only conforms to the S-stereochemistry. The β-cyclodextrin derivative 2f was hydrolyzed and converted to the methyl glycoside to give the minor R-isomer 5a.
Oxidation of secondary alcohols to the β-cyclodextrin ketone 4, 7e and 7f followed by reaction with organometallic reagents to give tertiary alcohols.
Oxidation of secondary alcohols to the β-cyclodextrin ketone 4, 7e and 7f followed by reaction with organometallic reagents to give tertiary alcohols.
Trifluoroacetic acid
CAS number: 76-05-1
Trifluoroacetic acid is a monocarboxylic acid that is the trifluoro derivative of acetic acid. It has a role as a reagent and a human xenobiotic metabolite.
Synthesis of 6c. Mes: 2,4,6-trimethylphenyl, TFA: trifluoroacetic acid.
Synthesis of 6c. Mes: 2,4,6-trimethylphenyl, TFA: trifluoroacetic acid.
Synthesis of β-LEAP. DIPEA=N,N’-diisopropylethylamine, NMM=4-methylmorpholine, HATU=O-(7-azabenzotriazol-1-yl)-N,N,N’,N’-tetramethyluronium hexafluorophosphate, TEA=triethylamine, TFA=trifluoroacetic acid.
Synthesis of β-LEAP. DIPEA=N,N’-diisopropylethylamine, NMM=4-methylmorpholine, HATU=O-(7-azabenzotriazol-1-yl)-N,N,N’,N’-tetramethyluronium hexafluorophosphate, TEA=triethylamine, TFA=trifluoroacetic acid.
Iodine-mediated oxidation of ynamides (Boc = tert-butoxycarbonyl, TFA = trifluoroacetic acid).
Iodine-mediated oxidation of ynamides (Boc = tert-butoxycarbonyl, TFA = trifluoroacetic acid).
Perchloric acid
CAS number: 7601-90-3
Perchloric acid is a strong acid used for complete digestions of organic material. It is normally supplied in bottles of up to one gallon in capacity at 70-72% strength. In many respects, its hazards are similar to those of nitric acid, as both are strong oxidants.
FT-IR spectra of silica-supported perchloric acid (A), perchlorate anion (B), and SiO2 (C).
FT-IR spectra of silica-supported perchloric acid (A), perchlorate anion (B), and SiO2 (C).
Silica
CAS number: 7631-86-9
Silica is another name for the chemical compound composed of silicon and oxygen with the chemical formula SiO2, or silicon dioxide.
We prepared the perchlorate salt of (S)-3 by alkylation of (S)-R-methylthio-2-(p-tolylsulfinyl)toluene 1 with MeI in the presence of silver perchlorate. 7b The resulting salt (S)-3 was quantitatively isolated by simply filtering the crude reaction mixture through a pad of celite, followed by washing with CH2Cl2 and evaporation to dryness15 (Scheme 2).
We prepared the perchlorate salt of (S)-3 by alkylation of (S)-R-methylthio-2-(p-tolylsulfinyl)toluene 1 with MeI in the presence of silver perchlorate. 7b The resulting salt (S)-3 was quantitatively isolated by simply filtering the crude reaction mixture through a pad of celite, followed by washing with CH2Cl2 and evaporation to dryness15 (Scheme 2).
Catalyst-armed Silica- and Co/C magnetic nanoparticles.
Catalyst-armed Silica- and Co/C magnetic nanoparticles.
Specular X-ray diffraction data of the OTS-covered Si/SiO2 substrate and of thin films of 2 deposited at different substrate temperatures.
Specular X-ray diffraction data of the OTS-covered Si/SiO2 substrate and of thin films of 2 deposited at different substrate temperatures.
Cis-beta-methylstyrene
CAS number: 766-90-5
Cis-beta-methylstyrene (also known as (Z)-1-phenyl-1-butene) is an organic compound belonging to the class of alkenylbenzenes. It features a styrene-like structure with a methyl group attached to the beta-carbon of the vinyl side chain in the cis (Z) configuration, meaning the phenyl ring and the methyl group are on the same side of the double bond.
LED-mediated cyclopropane synthesis. [a] Using trans-b-methylstyrene. [b] Using cis-b-methylstyrene. [c] 20 equiv of styrene. [d] Violet LED used. Also 27% of malonate dimer by H NMR. 1[e] Using soluble ylide 1o.
LED-mediated cyclopropane synthesis. [a] Using trans-b-methylstyrene. [b] Using cis-b-methylstyrene. [c] 20 equiv of styrene. [d] Violet LED used. Also 27% of malonate dimer by H NMR. 1[e] Using soluble ylide 1o.
Phosphoric acid
CAS number: 7664-38-2
Phosphoric acid (H3PO4) is a colorless syrupy liquid. It is also known as orthophosphoric acid and its available analytical grade is 85%. Phosphoric acid is made from the mineral phosphorus, which is found naturally in many foods.
Concept of Dual Catalytic Gold and Organic Phosphoric Acid Enantioselective Cyclization Cascade
Concept of Dual Catalytic Gold and Organic Phosphoric Acid Enantioselective Cyclization Cascade
Chiral phosphoric acid catalysts.
Chiral phosphoric acid catalysts.
N,N-diallyl-p-toluenesulfonamide (5) was cycloisomerized in [D8]toluene (0.17 m) at 50 °C in the presence of B (5 mol%) and 2b (1 equiv). The relative contents of B, G and decomposition products were estimated by 31P NMR spectroscopy with H3PO4 (85%) as external standard and 1,2;5,6-dibenzanthracene (5 mol%) as internal standard.
N,N-diallyl-p-toluenesulfonamide (5) was cycloisomerized in [D8]toluene (0.17 m) at 50 °C in the presence of B (5 mol%) and 2b (1 equiv). The relative contents of B, G and decomposition products were estimated by 31P NMR spectroscopy with H3PO4 (85%) as external standard and 1,2;5,6-dibenzanthracene (5 mol%) as internal standard.
BINOL-derived chiral phosphoric acid-catalyzed enantioselective B-V reaction of 3-substituted cyclobutanones
BINOL-derived chiral phosphoric acid-catalyzed enantioselective B-V reaction of 3-substituted cyclobutanones
3,3-Bis(4-hydroxyphenyl)phthalide
CAS number: 77-09-8
3,3-Bis(4-hydroxyphenyl)phthalide, also known as bisphenol A phthalide, is an organic compound characterized by its structure, which includes two hydroxyphenyl groups attached to a phthalide moiety. It is typically a white to off-white crystalline solid at room temperature.
Color development mechanism of phenolphthalein in alkaline solution
Color development mechanism of phenolphthalein in alkaline solution
Dimethyl sulfate
CAS number: 77-78-1
Dimethyl sulfate is a colorless oily liquid, odorless to a faint onion-like odor. It is very toxic by inhalation.
i) dimethyl sulfate, K2CO3, acetone, reflux; ii) NBS, AIBN, CCl4, reflux; iii) Br2, CHCl3, room temperature; iv) 1) Na2SO3·9H2O, ethanol, reflux; 2) Oxone, grade I alumina, CHCl3, reflux
i) dimethyl sulfate, K2CO3, acetone, reflux; ii) NBS, AIBN, CCl4, reflux; iii) Br2, CHCl3, room temperature; iv) 1) Na2SO3·9H2O, ethanol, reflux; 2) Oxone, grade I alumina, CHCl3, reflux
(-)-Quinic acid
CAS number: 77-95-2
Quinic acid is a cyclohexanecarboxylic acid contained in the extracts of several parts of medicinal plants including Haematocarpus validus, Hypericum empetrifolium, Achillea pseudoaleppica, Rumex nepalensis, Phagnalon saxatile subsp. saxatile, Coffea arabica, Ziziphus lotus L, and Artemisia annua L … etc.
Synthesis of (+)-9 from (−)-Quinic Acid
Synthesis of (+)-9 from (−)-Quinic Acid