Propargylamine is a colorless, odorless liquid that is known for its unique combination of an alkyne (triple bond) and an amine group, making it a versatile building block in organic synthesis and a valuable component in medicinal chemistry.
2-Amino-3-cyanopyridine is known for its reactivity and use as an intermediate in the synthesis of various heterocyclic compounds. It features a pyridine ring with an amino group at the 2-position and a cyano group at the 3-position.
Effect of reaction time on the preparation of 2-amino-3-cyano-pyridine 3a.
Benzenamine, 2,6-bis(1-methylethyl)- is a chemical compound also known as 2,6-Diisopropylaniline. It is an aromatic amine with two isopropyl groups attached to the benzene ring at positions 2 and 6.
The reaction of glyoxal with 2,6-diisopropylaniline in the presence of triethylamine.
1,3,4-Oxadiazoline is a five-membered heterocyclic compound containing one oxygen atom and two nitrogen atoms in the ring. It's a derivative of oxadiazole, where one of the double bonds in the oxadiazole ring is reduced. This class of compounds is known for its diverse pharmacological properties and is often studied for potential applications in medicinal chemistry.
Design strategy of 1,3,4-oxadiazoline derivatives containing urea moiety.
The possible mechanism of cyclcondensation reaction with substituted benzoylisocyanate to afford 1,3,4-oxadiazolines.
Cyclopenta[b]pyrrole is an organic chemical compound, specifically a heterocyclic aromatic compound, that features a fused five-membered ring (cyclopentane) and a pyrrole ring. It is also classified as an azapentalene.
Selected examples of bioactive cyclopenta[b]pyrroles.
Straightforward strategy for accessing cyclopenta[b]pyrroles.
Pyrrolo[3,2-b]pyrrole is a bicyclic aromatic heterocyclic compound composed of two fused pyrrole rings. It's known for its high electron density, ease of functionalization, and structural symmetry, making it a valuable building block in various applications, particularly in organic electronics and optoelectronics.
Tesaglitazar is a dual peroxisome proliferator-activated receptor (PPAR) agonist, with hypoglycemic activity. Tesaglitazar is more potent on the gamma subtype than on the alpha subtype of PPAR. This agent improves atherogenic dyslipidemia but may cause an increase in fibrosarcoma formation.
Fortunolide A is a norditerpenoid, specifically a 17-nor-cephalotane-type diterpenoid, isolated from the seeds of the Cephalotaxus fortunei var. alpine plant. It's known for its cytotoxic activity against certain tumor cell lines. It contains a unique tropone ring and a bridged lactone.
Cephalotaxus norditerpenes and strategies to the core structure: Harringtonolide, Fortunolide A, Fortunolide B, Hainanolide.