What is the role of mifepristone and misoprostol in the management of early pregnancy loss (EPL)?

Label:chem

Topic
Mifepristone is a progesterone antagonist that stops the pregnancy by blocking the effects of progesterone, a hormone necessary for maintaining pregnancy.
Answer
The study investigates the use of mifepristone pre-treatment followed by two doses of misoprostol for the medical management of early pregnancy loss. This protocol aims to achieve a high expulsion rate of the gestational sac, thereby providing a safe and effective alternative to surgical management (dilatation and curettage, D&C).
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