What are the barriers to the use of mifepristone for EPL management in assisted reproductive technology (ART) pregnancies?

Label:chem

Topic
ART pregnancies may have different hormonal profiles compared to naturally conceived pregnancies, which can affect the effectiveness of mifepristone. The presence or absence of a corpus luteum and the use of exogenous progesterone supplementation can influence the availability of progesterone receptors targeted by mifepristone.
Answer
Barriers to using mifepristone in ART pregnancies include the potential lack of a corpus luteum and varying levels of exogenous progesterone supplementation. These factors can affect the presence of progesterone receptors, potentially reducing the effectiveness of mifepristone. Further evaluation is needed to optimize its use in this specific context.
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