What is the role of mifepristone in the management of early pregnancy loss (EPL)?

Label:chem

Topic
Mifepristone is a progesterone receptor antagonist that, when used in combination with misoprostol, has been shown to be significantly more effective than misoprostol alone in managing EPL. It works by causing decidual necrosis and detachment of the pregnancy, facilitating the expulsion of pregnancy tissue.
Answer
Mifepristone is used to enhance the effectiveness of medical management of EPL when combined with misoprostol. It increases the success rate of expulsion and reduces the need for procedural evacuation. However, its use is limited due to regulatory restrictions and access issues.
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