What are the potential applications of SERS in clinical diagnostics and point-of-care (POC) screening?

Label:chem

Topic
SERS, combined with tailored nanoparticle substrates, offers a promising approach for the rapid detection of bacterial metabolites and stress markers. The study demonstrates the feasibility of using SERS for qualitative detection of bacterial stress using cost-effective and easily synthesized nanoparticles.

From: "Surface-Enhanced Raman Spectroscopy for Adenine Detection in Five Selected Bacterial Strains Under Stress Conditions", Sensors 2025, 25(15), 4629;
Answer
SERS has the potential to streamline bacterial identification and accelerate antibiotic susceptibility testing in clinical settings. It can be integrated into point-of-care (POC) diagnostic tools, providing a simpler, faster, and more accessible method for detecting bacterial metabolites and stress markers. This could improve patient outcomes and support antimicrobial stewardship by enabling rapid and accurate diagnosis of bacterial infections.
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