How does melatonin potentially reduce the risk of cataracts?

Label:chem

Topic
Melatonin has been shown to have antioxidant and anti-inflammatory effects, which can counteract oxidative stress. Oxidative stress drives cataractogenesis by promoting protein aggregation, lens opacification, and epithelial cell apoptosis.

From: "Association Between Melatonin Use and Cataract Risk: A Target Trial Emulation Retrospective Cohort Study", Antioxidants 2025, 14(8), 1016;
Answer
Melatonin may reduce the risk of cataracts by scavenging reactive oxygen species and stabilizing mitochondrial function, thereby reducing oxidative stress and inflammation in the lens.
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