How does quinagolide affect cell proliferation and apoptosis in the mammary gland?

Label:chem

Topic
The study assesses the effects of quinagolide on cell turnover in the mammary gland by measuring cell proliferation (using PCNA) and apoptosis (using TUNEL assay).
Answer
Quinagolide treatment reduces cell proliferation (PCNA-positive cells) and increases apoptosis (TUNEL-positive cells) in the mammary gland. This indicates that inhibiting PRL release with quinagolide leads to decreased cell activity and survival in the mammary tissue.
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