How does prolactin (PRL) influence mammary cell activity and milk production?

Label:chem

Topic
Prolactin is a hormone released during milking that is traditionally presumed to play a major role in maintaining lactation. The study explores the effects of inhibiting PRL release on mammary cell functions.
Answer
Prolactin stimulates milk protein synthesis and protects MEC from apoptosis. Inhibiting PRL release with quinagolide reduces milk yield, milk protein mRNA levels, and cell proliferation while increasing apoptosis in the mammary gland.
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