What is the role of quinagolide in treating endometriosis?

Label:chem

Topic
Endometriosis is an estrogen-dependent disease characterized by the presence of endometrial-like tissue outside the uterus, often associated with chronic pelvic pain and infertility. Quinagolide is a non-ergot derived selective dopamine receptor type-2 (DRD2) agonist proposed to inhibit angiogenesis via the vascular endothelial growth factor (VEGF) receptor 2.
Answer
Quinagolide inhibits the VEGF signaling pathway, which is involved in the development and maintenance of endometriotic lesions. By reducing angiogenesis, quinagolide may help prevent the further development of new lesions and reduce the size of existing ones.
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