What is the role of cisplatin in the aMVAC regimen?

Label:chem

Topic
Cisplatin is a critical component of the aMVAC regimen and is known for its activity in treating urothelial cancers.
Answer
Cisplatin is an essential chemotherapeutic agent in the aMVAC regimen. It helps achieve complete pathological responses in patients with muscle-invasive urothelial cancer. A study found that any reduction in the cisplatin dose significantly decreased the likelihood of achieving a complete pathological response.
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