What is the optimal preload timing for isomaltulose (ISO) to enhance the second meal effect (SME)?

Label:chem

Topic
A study explores the effect of preload timing (1 hour vs. 3 hours) of ISO or SUC snacks on incretin responses and postprandial metabolism.
Answer
A 3-hour preload of ISO is more effective than a 1-hour preload in enhancing PYY secretion and the second meal effect (SME), indicating that timing of ISO consumption significantly influences PYY secretion and improves postprandial glucose control.
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