What are the key chemical constituents identified in the flavonoid extract of Senecio scandens (SSF), and how were they analyzed?

Label:chem

Topic
SSF is derived from the aerial parts of Senecio scandens, a traditional medicinal plant rich in flavonoids. The extract was prepared using ethanol extraction followed by purification via macroporous resin.
Answer
Twenty flavonoids were identified in SSF using UHPLC/Q-Orbitrap/HRMS, with six prototype compounds (quercetin-3β-D-glucoside, rutin, kaempferol, kaempferol-3-O-rutinoside, quercetin, and afzelin) detected in the blood. The total flavonoid content was quantified spectrophotometrically at 510 nm using rutin as a standard.
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