How does almorexant affect spermatogenesis in healthy male subjects?

Label:chem

Topic
A study assessed the impact of almorexant on spermatogenesis, including sperm concentration, motility, and morphology.
Answer
A 4-week treatment with almorexant 200 mg did not elicit any discernible effect on sperm concentration, motility, or morphology. The mean concentration of spermatozoa decreased slightly, but the proportion of spermatozoa with normal morphology increased in both the almorexant and placebo groups. No significant differences were observed between the treatment groups.
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