What is the antibacterial activity of Ag/AgCl nanoparticles synthesized with different sugar ligands against multidrug-resistant Escherichia coli?

Label:chem

Topic
Multidrug-resistant bacterial infections pose a significant challenge to public health. This study evaluates the antibacterial activity of Ag/AgCl nanoparticles synthesized with different sugar ligands (LMA, G5AS, LSA, and LPSA) against multidrug-resistant Escherichia coli species.
Answer
The Ag/AgCl nanoparticles synthesized with different sugar ligands showed promising antibacterial activity against multidrug-resistant Escherichia coli species. LPSA and LSA synthesized formulations exhibited better antibacterial activity compared to G5AS and LMA synthesized ones, with minimum inhibitory concentrations (MIC) and minimum bactericidal concentrations (MBC) in the μg/mL range. The presence of L-Arginine enhanced the antibacterial activity, independent of the sugar ligand chemistry and nanoparticle morphology and size.
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