Which specific genes were differentially expressed in responders versus non-responders before lanreotide treatment?

Label:chem

Topic
A study identified key genes that were differentially expressed in T cell subsets from NET patients who responded to lanreotide compared to those who did not.
Answer
Genes such as TXNIP (thioredoxin-interacting protein), POU2F2 (Oct-2), and IGF1R were found to be differentially expressed in responders versus non-responders. TXNIP was lower in responders across all T cell subsets, while POU2F2 was lower in Th cells and IGF1R was higher in Treg cells of non-responders.
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