How does lanreotide treatment affect T cell signaling pathways in vivo?

Label:chem

Topic
A study examined the effects of lanreotide on signaling pathways in T cells from NET patients.
Answer
Lanreotide treatment upregulated genes involved in T cell receptor (TCR) signaling, Ras signaling, and PI3K-Akt signaling pathways in both responders and non-responders. However, the effects were more pronounced in responders, suggesting that lanreotide may enhance T cell activation and differentiation in these patients.
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