How does vitamin E supplementation affect cognitive performance in humans?

Label:chem

Topic
Cognitive performance refers to an individual’s ability to acquire, process, store, and retrieve information, encompassing domains such as memory, attention, executive function, language, and visuospatial skills. Vitamin E, particularly α-tocopherol, has been studied for its potential effects on cognitive performance.

From: "Shifting Perspectives on the Role of Tocotrienol vs. Tocopherol in Brain Health: A Scoping Review", Int. J. Mol. Sci. 2025, 26(13), 6339;
Answer
Vitamin E supplementation, especially with α-tocopherol, has been shown to improve cognitive performance in some studies, particularly in domains such as memory and executive function. However, results are inconsistent, and the efficacy of vitamin E supplementation on cognitive performance may depend on factors such as dosage, duration of supplementation, and baseline cognitive status.
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