What is the role of Nimodipine in treating severe refractory cerebral vasospasm (VSP) following aneurysmal subarachnoid hemorrhage (aSAH)?

Label:chem

Topic
Nimodipine is a calcium channel blocker that has been shown to be effective in preventing cerebral vasospasm. It is commonly used in the management of aSAH and has been used intraarterially in this study as part of the rescue therapy protocol.
Answer
Nimodipine is used to prevent and treat cerebral vasospasm by blocking calcium channels, thereby reducing vasospasm. In this study, it is administered intraarterially before Milrinone to provide an initial vasodilatory effect, which is then supplemented by the additional vasodilatory effect of Milrinone.
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