What is the effect of huperzine-A on the neuronal behavior of Drosophila melanogaster in cadmium chloride-induced neurotoxicity?

Label:chem

Topic
Drosophila melanogaster is a commonly used model organism for studying neurodegenerative diseases due to its genetic similarity to humans. Cadmium chloride induces neurotoxicity and alters neuronal behavior in flies.
Answer
Huperzine-A significantly improves neuronal behavior in cadmium chloride-induced Drosophila melanogaster, as evidenced by enhanced feeding, climbing, and reduced rough eye phenotype. This suggests that huperzine-A has a neuroprotective effect by mitigating the behavioral deficits caused by cadmium chloride.
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