What is the role of sertaconazole in the treatment of facial seborrheic dermatitis?
Label:chem
Topic
Sertaconazole is an imidazole antifungal agent used in the treatment of seborrheic dermatitis (SD), a chronic inflammatory skin condition often associated with Malassezia infection.
Answer
Sertaconazole inhibits the synthesis of ergosterol in the cell wall of fungi, reducing Malassezia proliferation and inflammation, thereby improving SD lesions. It has been shown to be as effective as hydrocortisone 1% cream in clearing SD lesions, with fewer adverse events.
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