How does pentosidine affect the levels of specific metabolites in adipose tissue?

Label:chem

Topic
A study identified several differential metabolites in adipose tissue of rats exposed to pentosidine, which were categorized into amino acids, fatty acids, carbohydrates, carboxylic acids, steroids, and other metabolites.
Answer
Pentosidine exposure significantly altered the levels of various metabolites in adipose tissue. For example, pyruvic acid and inositol levels increased, while petroselinic acid and D-glucuronic acid levels decreased. These changes were dose-dependent, indicating that pentosidine exposure can lead to significant disruptions in the metabolic balance of adipose tissue. The most notable changes were observed in fatty acids and amino acids, suggesting that pentosidine primarily affects energy and lipid metabolism.
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