What is the nucleation mechanism of p-methoxybenzoic acid (PMBA) in an ethanol-water system at different saturation temperatures?
Label:chem
Topic
PMBA is a naturally occurring metabolite used in dermatological drugs and cosmetics. Understanding its nucleation behavior is important for controlling crystallization processes.
Answer
At low saturation temperatures, PMBA follows a progressive nucleation mechanism (nucleation order m = 3.18–7.50), whereas at high saturation temperatures, it follows an instantaneous nucleation mechanism (m = 1.46–2.55).
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