What is the role of horseradish peroxidase (HRP) in the electrochemical biosensor for detecting trichloroacetic acid (TCA) and sodium nitrite (NaNO2)?

Label:chem

Topic
Horseradish peroxidase (HRP) is an enzyme known for its catalytic ability in redox reactions, making it a suitable candidate for electrochemical biosensors. However, the electroactive center of HRP is typically hindered by the protein chains, limiting its electron transfer efficiency.
Answer
In the electrochemical biosensor for detecting TCA and NaNO2, HRP serves as the catalytic component that facilitates the redox reactions necessary for detecting these analytes. The HRP is immobilized on the MWCNTs-BP nanocomposite-modified electrode, which enhances its electron transfer efficiency by providing a direct communication pathway between the enzyme's active center and the electrode surface. This results in improved sensitivity and detection limits for TCA and NaNO2.
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