How does haloperidol affect the morphology of zebrafish embryos at sub-lethal doses?

Label:chem

Topic
Haloperidol is known to induce various adverse effects in humans, including developmental toxicity. Understanding its impact on embryonic morphology is crucial for assessing potential risks during pregnancy.
Answer
At sub-lethal doses, haloperidol induces several deformities in zebrafish embryos, including abnormal somites, yolk sac edema, and skeletal deformities. These effects are dose-dependent and significant from 0.25 mg/L.
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