How did escitalopram affect the acquisition and expression of conditioned fear in rats?

Label:chem

Topic
Some study compared escitalopram's effects on fear acquisition and expression with those of 5-HTP and fenfluramine.
Answer
Escitalopram at a dose of 30 mg/kg administered prior to acquisition did not influence freezing during shock exposure or the expression of conditioned fear. Escitalopram did not significantly impact the expression of conditioned fear at any of the tested doses (3, 10, and 30 mg/kg) when administered before exposure to the conditioned context.
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