What is disulfiram primarily used for and what new treatment potential has been identified?

Label:chem

Topic
Disulfiram is an FDA-approved drug. Researchers have evaluated existing FDA-approved drugs for new therapeutic applications.
Answer
Disulfiram, also known as Antabuse, is primarily approved to support the treatment of chronic alcoholism, where it targets the enzyme acetaldehyde dehydrogenase to inhibit the breakdown of acetaldehyde. This study identified disulfiram as a candidate compound for a novel treatment for aggressive leukemia, based on its antileukemic activity.
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