What is the significance of the solvent medium in the oxidation reactions involving (diacetoxyiodo)benzene?

Label:chem

Topic
A study examines the effect of different solvents on the oxidation reactions of 3,5-di-tert-butylcatechol and 2-aminophenol by (diacetoxyiodo)benzene.
Answer
The solvent medium plays a crucial role in the oxidation reactions. In protic solvents like methanol, the reaction rates are significantly higher compared to aprotic solvents like acetonitrile. This is attributed to the formation of reactive intermediates and the stabilization of radicals by the solvent. The presence of methanol, in particular, results in a substantial increase in reaction rates due to the formation of methoxy radicals.
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