What are the implications of the hydrogen peroxide and organic peroxide content in pharmaceutical excipients and food samples?

Label:chem

Topic
The content of hydrogen peroxide and organic peroxides in pharmaceutical excipients and food samples can impact product quality and safety. Understanding their levels is important for formulation development and quality control.
Answer
The study found significant disparities in the content of hydrogen peroxide and organic peroxides in different samples. Hydrophilic samples like HPMC, MCC, and honey predominantly contained hydrogen peroxide, while more lipophilic samples like vegetable oil and milk were characterized by the presence of organic peroxides. This variation is attributed to factors such as synthesis processes, storage conditions, and sample age. The content of peroxides in these materials can influence their suitability for specific applications. For instance, high levels of hydrogen peroxide in excipients can lead to oxidation of active pharmaceutical ingredients, while organic peroxides in food products can affect shelf life and safety.
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