What is the role of vinblastine in the treatment of Hodgkin's lymphoma?

Label:chem

Topic
Vinblastine is a vinca alkaloid that inhibits microtubule formation, leading to cell cycle arrest and apoptosis.
Answer
Vinblastine is included in both BV-AVD and ABVD regimens to disrupt the microtubule dynamics in cancer cells, thereby preventing cell division and promoting cell death.
Return to Home Chemical List
Knowledge you may be interested in
How does doxorubicin contribute to the treatment of Hodgkin's lymphoma in both BV-AVD and ABVD regimens? What is the role of Brentuximab vedotin in the treatment of advanced-stage Hodgkin's lymphoma? What is the significance of cisplatin in both dd-MVAC and GC chemotherapy regimens? What is the role of peg-filgrastim in the dd-MVAC chemotherapy regimen? What are the main components of the gemcitabine and cisplatin (GC) chemotherapy regimen? What are the key components of the dose-dense methotrexate, vinblastine, doxorubicin, and cisplatin (dd-MVAC) chemotherapy regimen? What is the role of ciliobrevin A (CilioA) in modulating cancer cell resistance to VBL? What is the role of NPHP3 in primary cilium formation and cancer cell resistance? What role does vinblastine (VBL) play in cancer cell resistance? How is carboplatin dosing calculated in the DD-MVACarbo regimen? What is the role of dacarbazine in the treatment of Hodgkin's lymphoma? What are the potential side effects of bleomycin, and why is it not included in the BV-AVD regimen? What are the potential side effects of Brentuximab vedotin? What is the significance of the ABE segment in the synthesis of (-)-halenaquinone? What is the function of methylguaiacol (8) in the synthesis of (-)-halenaquinone? What is the role of 4,7-dimethoxyisobenzofuran (5) in the synthesis of (-)-halenaquinone? What is the role of trifluoroacetic acid (TFA) in the synthesis of (-)-halenaquinone? What is the purpose of using p-chloranil in the synthesis of (-)-halenaquinone? What is the role of titanium tetrachloride (TiCl4) in the synthesis of (-)-halenaquinone? What is the new halenaquinone derivative isolated from the tropical marine sponge Xestospongia sp.?