What is the significance of using a TBDMS group in the C3-chlorination of benzo[b]thiophene derivatives?

Label:chem

Topic
Protecting groups are often used in organic synthesis to prevent unwanted reactions at specific sites.
Answer
The TBDMS (tert-butyldimethylsilyl) group is used to protect the alcohol group in benzo[b]thiophene derivatives, preventing its oxidation during the C3-chlorination reaction. This allows for higher yields of the desired chlorinated product.
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