What is the role of the model C ring boronate 15 in the synthesis of the CDE ring fragment of pectenotoxin-4?

Label:chem

Topic
The model C ring boronate 15 is used as a substitute for the real ABC ring fragment required in the synthesis of pectenotoxin-4. This model compound is crucial for studying the feasibility of the rhodium-catalysed vinyl 1,4-addition.
Answer
The model C ring boronate 15 serves as a surrogate for the ABC ring fragment in initial studies. It is used to optimize the rhodium-catalysed vinyl 1,4-addition reaction conditions with the model E ring enone 19. This allows the researchers to establish the viability of the proposed synthetic route before applying it to the actual ABC ring fragment.
Return to Home Chemical List
Knowledge you may be interested in
What is the role of Sharpless Asymmetric Dihydroxylation (SAD) in the synthesis of the CDE ring fragment of pectenotoxin-4? What is the role of rhodium-catalysed vinyl 1,4-addition in the synthesis of the CDE ring fragment of pectenotoxin-4? How does the in vitro metabolism of pectenotoxin-2 (PTX-2) in rat hepatocytes affect its oral toxicity? What are the major metabolites formed from pectenotoxin-2 (PTX-2) during in vitro metabolism by rat hepatocytes? What role does pectenotoxin-2 (PTX-2) play in marine biotoxin research? What is the distribution of toxins within the tissues of Mesodesma donacium? How are pectenotoxins transformed in Mesodesma donacium? What is the impact of L-pyroglutamic acid on the antioxidant capacity and radical scavenging activity compared to other phenolic acids? What are the effects of L-pyroglutamic acid on the production of phenolic acids and flavonoids by F. graminearum? How does L-pyroglutamic acid affect the expression of Tri genes in F. graminearum? What is the role of the model E ring enone 19 in the synthesis of the CDE ring fragment of pectenotoxin-4? What is the significance of the [5,6]-bicyclic ketal structure in the synthesis of pectenotoxin-4? What is the role of the E ring fragment 35 in the synthesis of the CDE ring fragment of pectenotoxin-4? What is the role of triethylborane (TEB) in the synthesis of graft copolymers of cod collagen? How does butyl acrylate (BA) contribute to the formation of graft copolymers with cod collagen? What is the significance of vinyl butyl ether (VBE) in the graft copolymerization process? How does the presence of triethylborane (TEB) affect the structure of the resulting graft copolymer? What is the significance of the alternating copolymer structure formed by butyl acrylate (BA) and vinyl butyl ether (VBE)? What is the role of triethylborane (TEB) in the copolymerization of epoxides and anhydrides? What is the role of tetrabutylammonium chloride (TBACl) in the copolymerization process?