What is the role of the model E ring enone 19 in the synthesis of the CDE ring fragment of pectenotoxin-4?

Label:chem

Topic
The model E ring enone 19 is used in place of the desired E ring fragment in initial studies to investigate the feasibility of the rhodium-catalysed vinyl 1,4-addition and subsequent dihydroxylation-cyclisation sequence.
Answer
The model E ring enone 19 is used to study the reaction conditions and outcomes of the rhodium-catalysed vinyl 1,4-addition with the model C ring boronate 15. This helps in optimizing the reaction conditions and understanding the stereochemical outcomes before applying the methodology to the actual E ring fragment required for the synthesis of pectenotoxin-4.
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