What is the role of phenylboronic acid (PBA) in the functionalization of framboidal nanoparticles?
Label:chem
Topic
Phenylboronic acid (PBA) is a key component in the synthesis of framboidal nanoparticles (BNPs) and is used as a reactive group for post-modification to introduce different functional groups to the nanoparticles.
Answer
PBA groups on the BNPs enable the introduction of various functional groups through Suzuki–Miyaura cross-coupling reactions, allowing the nanoparticles to be used as versatile drug carriers.
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