Does absorbed silicon from diatomaceous earth (DE) accumulate in tissues and, if so, where?

Silicon is rapidly cleared from plasma and mainly excreted renally, but transient tissue deposition can occur.

After seven days of supplementation (2 or 4 mg Si kg⁻¹ day⁻¹), hepatic silicon rose ~4.7-fold (DE2) and ~3.3-fold (DE4) versus controls (1.89 ± 0.71 µg g⁻¹), confirming preferential liver accumulation; plasma silicon remained undetectable.